Carriers are protective transporters of drugs to target cells, facilitating therapy under each points of view, such as fast healing, reducing infective phenomena, and curing illnesses …
During the past few decades, supercritical fluid (SCF) has emerged as an effective alternative for many traditional pharmaceutical manufacturing processes. Operating active …
Ophthalmic drugs used for the treatment of various ocular diseases are commonly administered by eye drops. However, due to anatomical and physiological factors, there is a …
M Fathi, G Sodeifian, SA Sajadian - The Journal of Supercritical Fluids, 2022 - Elsevier
This study aims to increase the oral bioavailability of ketoconazole (KET, drug) by incorporating it into water-soluble polymers, using supercritical carbon dioxide (SC-CO 2) as …
ND Machado, JE Mosquera, RE Martini… - The Journal of …, 2022 - Elsevier
The loading of polymeric carriers with active pharmaceutical and nutraceutical ingredients using supercritical CO 2 (scCO 2) as solvent and diffusion enhancer has received increasing …
CJF Bertens, M Gijs, FJHM van den Biggelaar… - Experimental eye …, 2018 - Elsevier
For the treatment and prevention of ocular diseases, most patients are treated with conventional drug delivery formulations such as eye drops or ointments. However, eye …
A Ameri, G Sodeifian, SA Sajadian - The Journal of Supercritical Fluids, 2020 - Elsevier
This is the first work to load HPMC and PVP by the lansoprazole (LPZ) through supercritical solvent impregnation (SSI). The process was carried out at laboratory scale under various …
An increasing incidence of eye diseases has been registered in the last decades in developed countries due to the ageing of population, changes in lifestyle, environmental …