Background Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a minimally
invasive approach under investigation as a novel treatment for patients with peritoneal …

Theoretical considerations as well as comprehensive preclinical and clinical data suggest
that optimizing physical parameters of intraperitoneal drug delivery might help to circumvent …

Because peritoneal metastasis (PM) from ovarian cancer is characterized by non-specific
symptoms, it is often diagnosed at advanced stages. Pressurized intraperitoneal aerosol …

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is applied to treat unresectable
peritoneal metastasis (PM), an advanced, end-stage disease with a poor prognosis …

Postoperative peritoneal adhesions occur in the majority of patients undergoing intra-
abdominal surgery and are one of the leading causes of hospital re-admission. There is an …

Current therapies for patients with peritoneal metastases (PM) are only moderately effective.
Recently, a novel locoregional treatment method for PM was introduced, consisting of a …

Intraperitoneal (IP) aerosolized anticancer drug delivery was recently introduced in the
treatment of patients with peritoneal metastases. However, little is known on the effect of …

Background Hyperthermic intraperitoneal chemotherapy (HIPEC) is performed with a wide
variation in methodology, drugs, and other elements vital to the procedure. Adoption of a …

Background Systemic chemotherapy is not effective in patients with peritoneal
carcinomatosis (PC) and only a minority of affected patients is eligible for cytoreductive …

Intra-abdominal dissemination of peritoneal nodules, a condition known as peritoneal
carcinomatosis (PC), is typically diagnosed in ovarian cancer patients at the advanced …