The interplay between Ca 2+ and reactive oxygen species (ROS) signaling pathways is well
established, with reciprocal regulation occurring at a number of subcellular locations. Many …

It has long been known that endothelial Ca2+ signals drive angiogenesis by recruiting
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …

Vasculogenesis, angiogenesis and arteriogenesis represent three crucial mechanisms
involved in the formation and maintenance of the vascular network in embryonal and post …

Stim1 and Orai1 are ubiquitous proteins that have long been known to mediate Ca2+
release-activated Ca2+ (CRAC) current (ICRAC) and store-operated Ca2+ entry (SOCE) …

Endothelial progenitor cells (EPCs) home from the bone marrow to the site of tissue
regeneration and sustain neovascularization after acute vascular injury and upon the …

Ectopic thyroid tissue remains a rare developmental abnormality involving defective or
aberrant embryogenesis of the thyroid gland during its passage from the floor of the primitive …

Calcium (Ca2+) regulates a plethora of cellular functions including hallmarks of cancer
development such as cell cycle progression and cellular migration. Receptor-regulated …

Background Endothelial progenitor cells (EPCs) may be recruited from bone marrow to
sustain tumor vascularisation and promote the metastatic switch. Understanding the …

Endothelial colony forming cells (ECFCs) represent the most suitable cellular substrate to
induce revascularization of ischemic tissues. Recently, optical excitation of the light-sensitive …

Ca2+ acts as a universal and versatile second messenger in the regulation of a myriad of
biological processes, including cell proliferation, differentiation, migration and apoptosis …