Rotational thromboelastometry (ROTEM) is a point-of-care viscoelastic method and enables
to assess viscoelastic profiles of whole blood in various clinical settings. ROTEM-guided …

The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Blood loss and subsequent transfusions are associated with major morbidity and mortality.
The use of antifibrinolytics can reduce blood loss in cardiac surgery, trauma, orthopedic …

The effect of pregabalin on oxycodone consumption, post-operative confusion, and pain in
elderly cardiac surgery patients was investigated in a prospective, randomized, doubleblind …

Fibrinogen plays a critical role in achieving and maintaining hemostasis and is fundamental
to effective clot formation. There is increasing awareness of the important role of fibrinogen …

Introduction Viscoelastic assays have been promoted as an improvement over traditional
coagulation tests in the management of trauma patients. Rotational thromboelastometry …

There is wide variation in the management of coagulation and blood transfusion practice in
liver transplantation. The use of blood products intraoperatively is declining and transfusion …

Traumatic brain injury has long been associated with abnormal coagulation parameters, but
the exact mechanisms underlying this phenomenon are poorly understood. Coagulopathy …

Fibrinogen is a critical protein for hemostasis and clot formation. However, transfusion
guidelines have variable recommendations for maintaining fibrinogen levels in bleeding …

Antifibrinolytic drugs have become almost ubiquitous in their use during major surgery when
bleeding is expected or commonplace. Inhibition of the fibrinolytic pathway after tissue injury …