Perspectives of using microRNA-loaded nanocarriers for epigenetic reprogramming of drug resistant colorectal cancers

OA Sukocheva, J Liu, ME Neganova… - Seminars in Cancer …, 2022 - Elsevier
Epigenetic regulation by microRNAs (miRs) demonstrated a promising therapeutic potential
of these molecules to regulate genetic activity in different cancers, including colorectal …

Mast cells, microRNAs and others: the role of translational research on colorectal cancer in the forthcoming era of precision medicine

G Sammarco, G Gallo, G Vescio, A Picciariello… - Journal of Clinical …, 2020 - mdpi.com
Colorectal cancer (CRC) is a heterogeneous disease, molecularly and anatomically, that
develops in a multi-step process requiring the accumulation of several genetic or epigenetic …

Exosomes from microRNA‐126 overexpressing mesenchymal stem cells promote angiogenesis by targeting the PIK3R2‐mediated PI3K/Akt signalling pathway

L Zhang, P Ouyang, G He, X Wang… - Journal of Cellular …, 2021 - Wiley Online Library
Abstract microRNA‐126 (miR‐126), an endothelial‐specific miRNA, is associated with
vascular homeostasis and angiogenesis. However, the efficiency of miR‐126‐based …

Effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on ageing: molecular mechanisms

A Bahrami, S Bo, T Jamialahmadi, A Sahebkar - Ageing Research Reviews, 2020 - Elsevier
Human ageing is determined by degenerative alterations and processes with different
manifestations such as gradual organ dysfunction, tissue function loss, increased population …

Effect of curcumin and its derivates on gastric cancer: molecular mechanisms

A Bahrami, G A. Ferns - Nutrition and cancer, 2021 - Taylor & Francis
Gastric carcinoma is one of the most prevalent malignancies and is associated with a high
mortality. Chemotherapy is the principal therapeutic option in the treatment of gastric cancer …

NT5DC2 knockdown inhibits colorectal carcinoma progression by repressing metastasis, angiogenesis and tumor-associated macrophage recruitment: A mechanism …

Z Zhu, Q Hou, H Guo - Experimental Cell Research, 2020 - Elsevier
Colorectal cancer (CRC) is one of the most commonly diagnosed tumors among human
worldwide. Angiogenesis and tumor-associated macrophage (TAM) recruitment are closely …

Identification of cluster of differentiation molecule-associated microRNAs as potential therapeutic targets for gastrointestinal cancer immunotherapy

H Zhang, M Li, PJ Kaboli, H Ji, F Du… - … journal of biological …, 2021 - journals.sagepub.com
Background: Cluster of differentiation molecules are markers of immune cells that have been
identified as a potential immunotherapeutic target for cancer treatment. MicroRNAs are small …

[HTML][HTML] The dual role of microRNA-9 in gastrointestinal cancers: oncomiR or tumor suppressor?

A Bahrami, A Jafari, GA Ferns - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract microRNA are noncoding endogenous RNAs of∼ 25-nucleotide, involved in RNA
silencing and controlling of cell function. Recent evidence has highlighted the important role …

MicroRNA-34 and gastrointestinal cancers: a player with big functions

W Gao, J Zhou, M Morshedi - Cancer Cell International, 2024 - Springer
It is commonly assumed that gastrointestinal cancer is the most common form of cancer
across the globe and is the leading contributor to cancer-related death. The intricate …

Newcastle disease virus expressing an angiogenic inhibitor exerts an enhanced therapeutic efficacy in colon cancer model

F Meng, Y Cao, H Su, T Liu, L Tian, Y Zhang, J Yang… - Plos one, 2022 - journals.plos.org
Newcastle disease virus (NDV)-mediated gene therapy is a promising new approach for
treatment of cancer but shows limited anti-angiogenesis. VEGF-Trap plays a vital role in anti …