MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is
the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric …

Like many other viruses, KSHV has two life cycle modes: the latent phase and the lytic
phase. The RTA protein from KSHV is essential for lytic reactivation, but how this protein's …

Viral infection activates danger signals that are transmitted via the retinoic acid–inducible
gene 1–like receptor (RLR), nucleotide-binding oligomerization domain-like receptor (NLR) …

Kaposi's sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA virus with the
capacity to establish life-long latent infection. During latent infection, the viral genome …

Nuclear factor-κB (NF-κB) is an important transcription factor that induces the expression of
antiviral genes and viral genes. NF-κB activation needs the activation of NF-κB upstream …

Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …

N6-methyladenosine (m6A) is the most prevalent and internal modification of eukaryotic
mRNA. Multiple m6A methylation sites have been identified in the viral RNA genome and …

N6-methyladenosine (m6A), as a dynamic posttranscriptional RNA modification, recently
gave rise to the field of viral epitranscriptomics. The interaction between virus and host is …

Epstein–Barr virus (EBV) successfully persists in the vast majority of adults but causes
lymphoid and epithelial malignancies in a small fraction of latently infected individuals …