Amino acid transporters (AATs) are membrane-bound transport proteins that mediate
transfer of amino acids into and out of cells or cellular organelles. AATs have diverse …

The SLC6 family of secondary active transporters are integral membrane solute carrier
proteins characterized by the Na+-dependent translocation of small amino acid or amino …

Betaine and Na+ symport has been extensively studied in the osmotically regulated
transporter BetP from Corynebacterium glutamicum, a member of the betaine/choline …

Bilayer lipids contribute to the stability of membrane transporters and are crucially involved
in their proper functioning. However, the molecular knowledge of how surrounding lipids …

The Na+-coupled betaine symporter BetP senses changes in the membrane state and
increasing levels of cytoplasmic K+ during hyperosmotic stress latter via its C-terminal …

Transporters are integral membrane proteins with central roles in the efficient movement of
molecules across biological membranes. Many transporters exist as oligomers in the …

Solute carriers (SLC) that transport amino acids are key players in health and diseases in
humans. Their prokaryotic relatives are often involved in essential physiological processes …

Transmembrane proteins are responsible for transporting ions and small molecules across
the hydrophobic region of the cell membrane. We are reviewing the evidence for regulation …

A fundamental problem in computational biophysics is to deduce the function of a protein
from the structure. Many biological macromolecules such as enzymes, molecular motors or …

Several polytopic α-helical membrane-integrated proteins appear to be organized in higher-
ordered oligomeric complexes. While many aspects are still enigmatic, in recent years, the …