Reactive oxygen species in cancer: Current findings and future directions
H Nakamura, K Takada - Cancer science, 2021 - Wiley Online Library
Reactive oxygen species (ROS), a class of highly bioactive molecules, have been widely
studied in various types of cancers. ROS are considered to be normal byproducts of …
studied in various types of cancers. ROS are considered to be normal byproducts of …
Oxidatively induced DNA damage and its repair in cancer
M Dizdaroglu - Mutation Research/Reviews in Mutation Research, 2015 - Elsevier
Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …
Oxidatively induced DNA damage: mechanisms, repair and disease
M Dizdaroglu - Cancer letters, 2012 - Elsevier
Endogenous and exogenous sources cause oxidatively induced DNA damage in living
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …
Urinary biomarkers of oxidative status
D Il'yasova, P Scarbrough, I Spasojevic - Clinica chimica acta, 2012 - Elsevier
Oxidative damage produced by reactive oxygen species (ROS) has been implicated in the
etiology and pathology of many health conditions, including a large number of chronic …
etiology and pathology of many health conditions, including a large number of chronic …
[HTML][HTML] Biomarkers of nucleic acid oxidation–A summary state-of-the-art
Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …
Catalytic organometallic anticancer complexes
SJ Dougan, A Habtemariam… - Proceedings of the …, 2008 - National Acad Sciences
Organometallic complexes offer chemistry that is not accessible to purely organic molecules
and, hence, potentially new mechanisms of drug action. We show here that the presence of …
and, hence, potentially new mechanisms of drug action. We show here that the presence of …
Measurement and meaning of oxidatively modified DNA lesions in urine
Background: Oxidatively generated damage to DNA has been implicated in the
pathogenesis of a wide variety of diseases. The noninvasive assessment of such damage …
pathogenesis of a wide variety of diseases. The noninvasive assessment of such damage …
Cisplatin in the era of PARP inhibitors and immunotherapy
Platinum compounds such as cisplatin, carboplatin and oxaliplatin are widely used in
chemotherapy. Cisplatin induces cytotoxic DNA damage that blocks DNA replication and …
chemotherapy. Cisplatin induces cytotoxic DNA damage that blocks DNA replication and …
[HTML][HTML] Oxidative damage DNA: 8-oxoGua and 8-oxodG as molecular markers of cancer
K Roszkowski, W Jozwicki, P Blaszczyk… - … medical journal of …, 2011 - ncbi.nlm.nih.gov
Background The broad spectrum of oxidative damage DNA biomarkers: urinary excretion of
8-oxodG (8-oxo-7, 8-dihydro-2′-deoxyguanosine), 8-oxoGua (8-oxo-7, 8-dihydroguanine) …
8-oxodG (8-oxo-7, 8-dihydro-2′-deoxyguanosine), 8-oxoGua (8-oxo-7, 8-dihydroguanine) …
[HTML][HTML] APE1/Ref-1–one target with multiple indications: emerging aspects and new directions
In the realm of DNA repair, base excision repair (BER) protein, APE1/Ref-1
(Apurinic/Apyrimidinic Endonuclease 1/Redox Effector-1, also called APE1) has been …
(Apurinic/Apyrimidinic Endonuclease 1/Redox Effector-1, also called APE1) has been …