The gut harbors an enormous diversity of microbes that are essential for the maintenance of homeostasis in health and disease. A growing body of evidence supports the role of this …
Incretin peptides, principally GLP-1 and GIP, regulate islet hormone secretion, glucose concentrations, lipid metabolism, gut motility, appetite and body weight, and immune …
N Chaudhari, SD Roper - The Journal of cell biology, 2010 - ncbi.nlm.nih.gov
Taste buds are aggregates of 50–100 polarized neuroepithelial cells that detect nutrients and other compounds. Combined analyses of gene expression and cellular function reveal …
MY Pepino - Physiology & behavior, 2015 - Elsevier
Until recently, the general belief was that non-nutritive sweeteners (NNSs) were healthy sugar substitutes because they provide sweet taste without calories or glycemic effects …
P Besnard, P Passilly-Degrace… - Physiological …, 2016 - journals.physiology.org
An attraction for palatable foods rich in lipids is shared by rodents and humans. Over the last decade, the mechanisms responsible for this specific eating behavior have been actively …
W Kim, JM Egan - Pharmacological reviews, 2008 - ASPET
Incretins are gut hormones that are secreted from enteroendocrine cells into the blood within minutes after eating. One of their many physiological roles is to regulate the amount of …
AD Miras, CW Le Roux - Nature reviews Gastroenterology & hepatology, 2013 - nature.com
The clinical efficacy of bariatric surgery has encouraged the scientific investigation of the gut as a major endocrine organ. Manipulation of gastrointestinal anatomy through surgery has …
Abstract Glucagon-like peptide-1 (GLP-1), an incretin hormone, is released from intestinal L- cells in response to nutrients. GLP-1 lowers blood glucose levels by stimulating insulin …
The tongue is a complex multifunctional organ that interacts and senses both interoceptively and exteroceptively. Although it is easily visible to almost all of us, it is relatively …