Crohn's disease (CD) and ulcerative colitis (UC) are both highly inflammatory diseases of
the gastrointestinal tract, collectively known as inflammatory bowel disease (IBD). Although …

Polyphenols are naturally occurring compounds in plants and they are the most abundant
antioxidants in the human diet. Due to their considerable structural diversity, this largely …

Overproduction of reactive oxygen species (ROS), a key characteristic of inflammatory bowel
disease (IBD), is responsible for dysregulation of signal transduction, inflammatory …

The importance of gut microbiota in human health and pathophysiology is undisputable.
Despite the abundance of metagenomics data, the functional dynamics of gut microbiota in …

Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are
characterised by aberrant immunological responses leading to chronic inflammation without …

The cellular formation of reactive oxygen species (ROS) represents an evolutionary ancient
antimicrobial defense system against microorganisms. The NADPH oxidases (NOX), which …

Delivering drugs directly to the inflamed intestinal sites to treat inflammatory bowel disease
(IBD), particularly Crohn's and ulcerative colitis, is highly challenging. Recent advances in …

Ulcerative colitis (UC) is an inflammatory bowel disease with increasing incidence in the
world, especially in developing countries. Although knowledge of its pathogenesis has …

Inflammatory bowel disease (IBD), which includes both ulcerative colitis and Crohn's
disease, is a chronic relapsing inflammation of the gastrointestinal tract, and is difficult to …

Background Previous studies implicated matrix metalloproteinases (MMPs), such as MMP-7,
in inflammatory bowel diseases (IBD) by showing increased activity during inflammation of …