Transition-metal-catalyzed, coordination-assisted C (sp3)–H functionalization has
revolutionized synthetic planning over the past few decades as the use of these directing …

During the past decades, synthetic organic chemistry discovered that directing group
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …

C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

The present review is devoted to summarizing the recent advances (2015–2017) in the field
of metal-catalysed group-directed C–H functionalisation. In order to clearly showcase the …

Use of a directing group in C–H functionalizations, often referred to as chelation assistance,
is one of the most reliable methods for achieving highly efficient and highly site-selective …

Nickel-catalyzed C–H activation has become a predominant and ubiquitous research area
in organic chemistry. Direct functionalization of inert C–H bonds to create functionally …

During the last two decades, impressive advancements have been achieved in transition
metal‐catalyzed chelation‐assisted C—H functionalization reaction. While reactions in this …

In this study we report the identification of a novel class of ligands for palladium‐catalyzed C
(sp3)− H activation that enables the direct alkynylation of free carboxylic acid substrates. In …

C− C triple bonds are amongst the most versatile functional groups in synthetic chemistry.
Complementary to the Sonogashira coupling the direct metal‐catalyzed alkynylation of C− H …

The reaction of N-heteroaromatic compounds, such as 2-aryl-pyrrole, benzimidazole,
imidazole, indole, and pyrazole derivatives, with alkynes in the presence of a catalytic …