Introduction: Monoamine oxidase (MAO) inhibitors, despite the initial pharmacological
interest, are used in clinic for their antidepressant effect and in the management of …

Accumulating evidence shows a relationship between the human MAO-B (hMAO-B) enzyme
and neuropsychiatric/degenerative disorder, personality traits, type II alcoholism, borderline …

Introduction: Monoamine oxidase (MAO) plays an important role in the control of intracellular
concentration of monoaminergic neurotransmitters or neuromodulators and dietary amines …

Background Epigenetic markers such as DNA methylation of the monoamine oxidase A
(MAOA) gene have previously been shown to be altered in anxiety-and stress-related …

The deer mouse presents with spontaneous stereotypic movements that resemble the
repetitive behaviours of obsessive–compulsive disorder (OCD), and demonstrates a …

Rationale Impairments in behavioral flexibility lie at the core of anxiety and obsessive-
compulsive disorders. Few studies, however, have investigated the neural substrates of …

Aim Obsessive–compulsive disorder (OCD) is a disorder characterized by the presence of
obsessions and/or compulsions. Although disorder etiology and pathogenesis remains …

Lamotrigine is an anticonvulsant drug effective in the treatment of epilepsy and bipolar
depression. Preclinical data showed that lamotrigine inhibited monoamine oxidase (MAO) …

Several lines of evidence support the role of monoaminergic and cholinergic dysregulation
in attention deficit hyperactivity disorder (ADHD) and the concept that peripheral blood …

The role of serotonin in stress and anxiety, particularly in social environments, is not well
understood. Selective serotonin reuptake inhibitors are useful for patients that experience …