Lysosomes are ubiquitous membrane-bound intracellular organelles with an acidic interior.
They are central for degradation and recycling of macromolecules delivered by endocytosis …

Mitochondrial outer membrane permeabilization (MOMP) constitutes one of the major
checkpoint (s) of apoptotic and necrotic cell death. Recently, the permeabilization of yet …

The programmed removal of organelles from differentiating lens fibre cells contributes
towards lens transparency through formation of an organelle-free zone (OFZ). Disruptions in …

The elimination of unwanted cells by programmed cell death is a common feature of animal
development. Genetic studies in the nematode Caenorhabditis elegans, the fruit fly …

Epithelial ovarian cancer (EOC) is the leading cause of death from gynecologic
malignancies and has a poor prognosis due to relatively unspecific early symptoms, and …

The progress zone (PZ) is a specialized area at the distal margin of the developing limb
where mesodermal cells are kept in proliferation and undifferentiated, allowing limb …

This study re-examined the dying process in the interdigital tissue during the formation of
free digits in the developing limbs. We demonstrated that the interdigital dying process was …

Physiological cell death is a key mechanism that ensures appropriate development and
maintenance of tissues and organs in multicellular organisms. Most structures in the …

“Programmed cell death or 'apoptosis' is critical for organogenesis during embryonic
development and tissue homeostasis in the adult. Its deregulation can contribute to a broad …

Cancer remains a major and leading health problem worldwide. Lack of early diagnosis,
chemoresistance, and recurrence of cancer means vast research and development are …