Dendrimer-mediated delivery of DNA and RNA vaccines

LA Kisakova, EK Apartsin, LF Nizolenko, LI Karpenko - Pharmaceutics, 2023 - mdpi.com
DNA and RNA vaccines (nucleic acid-based vaccines) are a promising platform for vaccine
development. The first mRNA vaccines (Moderna and Pfizer/BioNTech) were approved in …

MicroRNAs-Based Theranostics against Anesthetic-Induced Neurotoxicity

R Minz, PK Sharma, A Negi, KK Kesari - Pharmaceutics, 2023 - mdpi.com
Various clinical reports indicate prolonged exposure to general anesthetic-induced
neurotoxicity (in vitro and in vivo). Behavior changes (memory and cognition) are …

Unsymmetrical Low-Generation Cationic Phosphorus Dendrimers as a Nonviral Vector to Deliver MicroRNA for Breast Cancer Therapy

Y Zou, S Shen, A Karpus, H Sun, R Laurent… - …, 2024 - ACS Publications
The development of nonviral dendritic polymers with a simple molecular backbone and
great gene delivery efficiency to effectively tackle cancer remains a great challenge …

Personalized nanovaccines for treating solid cancer metastases

T Feng, J Hu, J Wen, Z Qian, G Che, Q Zhou… - Journal of Hematology & …, 2024 - Springer
Cancer vaccines have garnered attention as a potential treatment for cancer metastases.
Nevertheless, the clinical response rate to vaccines remains< 30%. Nanoparticles stabilize …

Effects of Dendrimer-microRNA Nanoformulations against Glioblastoma Stem Cells

N Knauer, M Meschaninova, S Muhammad, D Hänggi… - Pharmaceutics, 2023 - mdpi.com
Glioblastoma is a rapidly progressing tumor quite resistant to conventional treatment. These
features are currently assigned to a self-sustaining population of glioblastoma stem cells …

Dendrimers for drug delivery: where do we stand in 2023?

EK Apartsin - Pharmaceutics, 2023 - mdpi.com
Dendrimers are highly symmetric, hyperbranched macromolecules consisting of repeating
structural units. Owing to their peculiar synthesis, the structure of dendrimers is perfectly …

Nanomaterial-Based Strategies for Attenuating T-Cell-Mediated Immunodepression in Stroke Patients: Advancing Research Perspectives

Y Wang, C Liu, Y Ren, J Song, K Fan… - International Journal …, 2024 - Taylor & Francis
This review article discusses the potential of nanomaterials in targeted therapy and
immunomodulation for stroke-induced immunosuppression. Although nanomaterials have …

Targeted Nanocarriers

DB Yalcinkaya, S Dogan, VC Ozalp, B Guvenc Tuna - 2024 - books.rsc.org
The advances in nanotechnology have resulted in transformative discoveries across diverse
scientific fields, particularly in drug delivery systems. Targeted nanocarriers, a pivotal …