Membrane barrels are taller, fatter, inside-out soluble barrels
Up-and-down β-barrel topology exists in both the membrane and soluble environment. By
comparing features of these structurally similar proteins, we can determine what features are …
comparing features of these structurally similar proteins, we can determine what features are …
Functional classification of membrane transporters and channels based on filtered TM/non‐TM amino acid composition
NS Schaadt, V Helms - Biopolymers, 2012 - Wiley Online Library
Membrane transporters catalyze the transport of small solute molecules across biological
barriers such as lipid bilayer membranes. As the experimental annotation of which proteins …
barriers such as lipid bilayer membranes. As the experimental annotation of which proteins …
TMBB-DB: a transmembrane β-barrel proteome database
TC Freeman Jr, WC Wimley - Bioinformatics, 2012 - academic.oup.com
Motivation: We previously reported the development of a highly accurate statistical algorithm
for identifying β-barrel outer membrane proteins or transmembrane β-barrels (TMBBs), from …
for identifying β-barrel outer membrane proteins or transmembrane β-barrels (TMBBs), from …
β‐Strand twisting/bending in soluble and transmembrane β‐barrel structures
N Kikuchi, K Fujiwara, M Ikeguchi - Proteins: Structure, Function …, 2018 - Wiley Online Library
The majority of β‐strands in globular proteins have a right‐handed twist and bend. The
dominant driving force for β‐strand twisting is thought to be inter‐strand hydrogen bonds …
dominant driving force for β‐strand twisting is thought to be inter‐strand hydrogen bonds …
Predicting structural and functional properties of membrane proteins from protein sequence
Integral transmembrane (TM) proteins are essential constituents of biological membranes
where they fulfill a variety of important cellular functions. Because of difficulties with …
where they fulfill a variety of important cellular functions. Because of difficulties with …
Computational systems biology methods for functional classification of membrane proteins and modeling of quorum sensing in Pseudomonas aeruginosa
NS Schaadt - 2013 - publikationen.sulb.uni-saarland.de
Due to the function of membrane proteins and the effort required for experimental
annotations, bioinformatical approaches to functionally classify uncharacterized sequences …
annotations, bioinformatical approaches to functionally classify uncharacterized sequences …
[PDF][PDF] Computational Systems Biology Methods
NS Schaadt - 2013 - scholar.archive.org
Due to the function of membrane proteins and the effort required for experimental
annotations, bioinformatical approaches to functionally classify uncharacterized sequences …
annotations, bioinformatical approaches to functionally classify uncharacterized sequences …
[图书][B] Modeling insertion of transmembrane beta-barrels for designing outer membrane proteins
D Hsieh - 2012 - search.proquest.com
Outer membrane proteins (OMPs) perform a range of important functions in the cell biology
of Gram-negative bacteria, mitochondria and chloroplasts. These functions include …
of Gram-negative bacteria, mitochondria and chloroplasts. These functions include …
[引用][C] Volkhard Helms, Ph. D., Professor of Bioinformatics
J Köhler - 2003 - Saarland University