ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

[PDF][PDF] Nanobody—A versatile tool for cancer diagnosis and therapeutics

M Liu, L Li, D Jin, Y Liu - Wiley Interdisciplinary Reviews …, 2021 - researchgate.net
In spite of the successful use of monoclonal antibodies (mAbs) in clinic for tumor treatment,
their applications are still hampered in therapeutic development due to limitations, such as …

Click chemistry and radiochemistry: an update

D Bauer, MA Cornejo, TT Hoang, JS Lewis… - Bioconjugate …, 2023 - ACS Publications
The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …

Near-infrared fluorescence imaging in immunotherapy

Y Ji, C Jones, Y Baek, GK Park, S Kashiwagi… - Advanced drug delivery …, 2020 - Elsevier
Near-infrared (NIR) light possesses many suitable optophysical properties for medical
imaging including low autofluorescence, deep tissue penetration, and minimal light …

Contemporary Approaches for Site‐Selective Dual Functionalization of Proteins

L Xu, SL Kuan, T Weil - Angewandte Chemie International …, 2021 - Wiley Online Library
Site‐selective protein functionalization serves as an invaluable tool for investigating protein
structures and functions in complicated cellular environments and accomplishing semi …

Emerging fluorescent molecular tracers to guide intra-operative surgical decision-making

P Debie, S Hernot - Frontiers in Pharmacology, 2019 - frontiersin.org
Fluorescence imaging is an emerging technology that can provide real-time information
about the operating field during cancer surgery. Non-specific fluorescent agents, used for …

PET/fluorescence imaging: An overview of the chemical strategies to build dual imaging tools

J Ariztia, K Solmont, NP Moïse, S Specklin… - Bioconjugate …, 2022 - ACS Publications
Molecular imaging is a biomedical research discipline that has quickly emerged to afford the
observation, characterization, monitoring, and quantification of biomarkers and biological …

Endogenous stimuli‐activatable nanomedicine for immune theranostics for cancer

W Wang, Y Jin, X Liu, F Chen, X Zheng… - Advanced Functional …, 2021 - Wiley Online Library
Cancer immunotherapy has witnessed significant advances in the past decade, however
challenges associated with immune‐related adverse effects and immunosuppressive tumor …

Cyanine conjugate‐based biomedical imaging probes

Y Li, Y Zhou, X Yue, Z Dai - Advanced Healthcare Materials, 2020 - Wiley Online Library
Cyanine is a class of fluorescent dye with meritorious fluorescence properties and has
motivated numerous researchers to explore its imaging capabilities by miscellaneous …

[HTML][HTML] Development of a radiolabeled site-specific single-domain antibody positron emission tomography probe for monitoring PD-L1 expression in cancer

Y Chen, S Zhu, J Fu, J Lin, Y Sun, G Lv, M Xie… - Journal of …, 2022 - Elsevier
Despite advances in immunotherapy for the treatment of cancers, not all patients can benefit
from programmed cell death ligand 1 (PD-L1) immune checkpoint blockade therapy. Anti-PD …