Comparative pathology of aging great apes: bonobos, chimpanzees, gorillas, and orangutans

LJ Lowenstine, R McManamon… - Veterinary …, 2016 - journals.sagepub.com
The great apes (chimpanzees, bonobos, gorillas, and orangutans) are our closest relatives.
Despite the many similarities, there are significant differences in aging among apes …

Age-related decline in executive function as a hallmark of cognitive ageing in primates: an overview of cognitive and neurobiological studies

A Lacreuse, N Raz, D Schmidtke… - … of the Royal …, 2020 - royalsocietypublishing.org
Executive function (EF) is a complex construct that reflects multiple higher-order cognitive
processes such as planning, updating, inhibiting and set-shifting. Decline in these functions …

Predicting age from cortical structure across the lifespan

CR Madan, EA Kensinger - European Journal of Neuroscience, 2018 - Wiley Online Library
Despite interindividual differences in cortical structure, cross‐sectional and longitudinal
studies have demonstrated a large degree of population‐level consistency in age‐related …

[HTML][HTML] Systematic cortical thickness and curvature patterns in primates

N Demirci, ME Hoffman, MA Holland - NeuroImage, 2023 - Elsevier
Humans are known to have significant and consistent differences in thickness throughout
the cortex, with thick outer gyral folds and thin inner sulcal folds. Our previous work has …

Cortical cell and neuron density estimates in one chimpanzee hemisphere

CE Collins, EC Turner, EK Sawyer… - Proceedings of the …, 2016 - National Acad Sciences
The density of cells and neurons in the neocortex of many mammals varies across cortical
areas and regions. This variability is, perhaps, most pronounced in primates. Nonuniformity …

Going beyond established model systems of Alzheimer's disease: companion animals provide novel insights into the neurobiology of aging

AA de Sousa, BA Rigby Dames, EC Graff… - Communications …, 2023 - nature.com
Alzheimer's disease (AD) is characterized by brain plaques, tangles, and cognitive
impairment. AD is one of the most common age-related dementias in humans. Progress in …

A comprehensive atlas of white matter tracts in the chimpanzee

KL Bryant, L Li, N Eichert, RB Mars - PLoS biology, 2020 - journals.plos.org
Chimpanzees (Pan troglodytes) are, along with bonobos, humans' closest living relatives.
The advent of diffusion MRI tractography in recent years has allowed a resurgence of …

Changes in Frontoparietotemporal Connectivity following Do-As-I-Do Imitation Training in Chimpanzees (Pan troglodytes)

SM Pope, JP Taglialatela, SA Skiba… - Journal of cognitive …, 2018 - direct.mit.edu
Human imitation is supported by an underlying “mirror system” principally composed of
inferior frontal, inferior parietal, and superior temporal cortical regions. Across primate …

Behavioral and brain asymmetries in primates: a preliminary evaluation of two evolutionary hypotheses

WD Hopkins, M Misiura, SM Pope… - Annals of the New York …, 2015 - Wiley Online Library
Contrary to many historical views, recent evidence suggests that species‐level behavioral
and brain asymmetries are evident in nonhuman species. Here, we briefly present evidence …

The association of astrogliosis and microglial activation with aging and Alzheimer's disease pathology in the chimpanzee brain

MK Edler, EL Munger, H Maycon… - Journal of …, 2023 - Wiley Online Library
Aging and neurodegenerative disorders, such as Alzheimer's disease (AD), trigger an
immune response known as glial activation in the brain. Recent evidence indicates species …