Regulation and dysregulation of the hypothalamic-pituitary-adrenal axis: The corticotropin-releasing hormone perspective

GP Chrousos - Endocrinology and metabolism clinics of North America, 1992 - Elsevier
This article is an up-to-date review of the impact that the discovery of corticotropin-releasing
hormone (CRH) has had on basic science and clinical medicine. It discusses hypothalamic …

Neuroendocrine circuits governing energy balance and stress regulation: functional overlap and therapeutic implications

YM Ulrich-Lai, KK Ryan - Cell metabolism, 2014 - cell.com
Significant comorbidities between obesity-related metabolic disease and stress-related
psychological disorders suggest important functional interactions between energy balance …

Stress produced by gavage administration in the rat

AP Brown, N Dinger, BS Levine - Journal of the American …, 2000 - ingentaconnect.com
This research project examined the relationship between gavage administration of various
vehicles and induction of the stress response, as defined by increased plasma …

Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus

L Rinaman - American Journal of Physiology-Regulatory …, 1999 - journals.physiology.org
This study tested the hypothesis that systemic stressors in rats activate glucagon-like peptide-
1 (GLP-1)-immunoreactive neurons in the caudal brain stem, including those that project to …

Brain corticotropin-releasing factor mediates 'anxiety-like'behavior induced by cocaine withdrawal in rats

Z Sarnyai, E Biro, J Gardi, M Vecsernyés, J Julesz… - Brain research, 1995 - Elsevier
Anxiety is a key symptom of the cocaine withdrawal syndrome in human addicts, and it is
considered to be one of the major factors in precipitating relapse to chronic cocaine abuse …

Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation

L Rinaman - Journal of Neuroscience, 2003 - Soc Neuroscience
Behavioral, autonomic, and endocrine outputs of the CNS are subject to important feedback
modulation by viscerosensory signals that are conveyed initially to the hindbrain nucleus of …

Cholecystokinin activates catecholaminergic neurons in the caudal medulla that innervate the paraventricular nucleus of the hypothalamus in rats

L Rinaman, GE Hoffman, J Dohanics… - Journal of …, 1995 - Wiley Online Library
Stimulation of gastric vagal afferents by systemic administration of cholecystokinin
octapeptide (CCK) inhibits gastric motility, reduces food intake, and stimulates pituitary …

[HTML][HTML] Neurohormonal regulation of appetite and its relationship with stress: A mini literature review

AH Ans, I Anjum, V Satija, A Inayat, Z Asghar, I Akram… - Cureus, 2018 - ncbi.nlm.nih.gov
Stress has long been known to affect eating behaviors in humans. Stress-induced
hyperphagia is considered a potential cause for the development of obesity. Given the high …

The role of nucleus of the solitary tract glucagon‐like peptide‐1 and prolactin‐releasing peptide neurons in stress: anatomy, physiology and cellular interactions

MK Holt, L Rinaman - British Journal of Pharmacology, 2022 - Wiley Online Library
Neuroendocrine, behavioural and autonomic responses to stressful stimuli are orchestrated
by complex neural circuits. The caudal nucleus of the solitary tract (cNTS) in the dorsomedial …

Biological basis of generalized anxiety disorder

O Brawman-Mintzer, RB Lydiard - Journal of Clinical Psychiatry, 1997 - psychiatrist.com
Despite the considerable revisions to diagnostic criteria, recent data indicate that
generalized anxiety disorder (GAD) is one of the most common anxiety disorders. Growing …