Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …

T cells and natural killer (NK) cells have complementary roles in tumor immunity, and dual T
cell and NK cell attack thus offers opportunities to deepen the impact of immunotherapy …

Surgical resection remains a mainstay in the treatment of malignant solid tumors. However,
the use of neoadjuvant treatments, including chemotherapy, radiotherapy, phototherapy …

Immune escape is a hallmark of cancer. The dynamic and heterogeneous tumour
microenvironment (TME) causes insufficient infiltration and poor efficacy of natural killer (NK) …

The inhibition of protein tyrosine phosphatases 1B (PTP1B) and N2 (PTPN2) has emerged
as an exciting approach for bolstering T cell anti-tumor immunity. ABBV-CLS-484 is a …

Natural killer (NK) cells are cytotoxic innate lymphocytes that eradicate tumor cells. Inducing
durable antitumor immune responses by NK cells represents a major priority of cancer …

The cGAS-STING signaling is an important pathway involved in the regulation of tumor
microenvironment, which affects many cellular functions including immune activation. Its role …

Myeloid immune cells (MICs) are potent innate immune cells serving as first responders to
invading pathogens and internal changes to cellular homeostasis. Cancer is a stage of …

Natural killer cells (NK) are innate lymphocytes endowed with the ability to recognize and kill
cancer cells. Consequently, adoptive transfer of autologous or allogeneic NK cells …

Innate immunity plays an important role not only during infection but also homeostatic role
during stress conditions. Activation of the immune system including innate immune response …