A dysregulated immune response characterized by the hyperproduction of several pro-
inflammatory cytokines (aka 'cytokine storm') plays a central role in the pathophysiology of …

Rheumatoid Arthritis (RA) is a chronic autoimmune condition characterized by symptoms of
inflammation and pain in the joints. RA is estimated to have a worldwide prevalence of 0.5 …

Objective Preliminary findings suggest a relationship between lower serum 25-
hydroxyvitamin D [25 (OH) D] levels and incidence and severity of COVID-19. The aim of this …

Omega-3 polyunsaturated fatty acids (PUFA) have demonstrated anti-inflammatory
properties, while Omega-6 have pro-inflammatory effects, and the balance between the two …

Introduction Over the last few months, coronavirus disease 2019 (COVID-19) pandemic
caused by the novel coronavirus SARS-CoV-2 has posed a serious threat to public health …

Some earlier studies reported higher risk of COVID-19 mortality in patients with vitamin D
deficiency, while some others failed to find such as association. Due to inconsistences …

Clinical islet transplantation has the potential to cure type 1 diabetes. Despite recent
therapeutic success, it is still uncommon because transplanted islets are damaged by …

Fatty acid metabolism contributes to energy supply and plays an important role in regulating
immunity. Free fatty acids (FFAs) bind to free fatty acid receptors (FFARs) on the cell surface …

Vitamin D, a key nutrient/prohormone classically associated with skeletal health, is also an
important immunomodulator, with pleotropic effects on innate and adaptive immune cells …

Type 1 diabetes (T1D) is a life-threatening condition for which islet transplantation offers a
way to extend longevity and vastly improve quality of life, but the degree and duration of …