Multiple macrophage products Paradoxically, the list of macrophage secretory products
(Table I) has not grown much longer in the lastfew years, despite con-tinual entries. The …

Since the discovery of scarless fetal skin wound healing, research in the field has expanded
significantly with the hopes of advancing the finding to adult human patients. There are …

Purpose Sipuleucel-T, the first FDA-approved autologous cellular immunotherapy for
treatment of advanced prostate cancer, is manufactured by activating peripheral blood …

The roles played by resident macrophages (Mφ) and mast cells (MCs) in polymorphonuclear
leukocyte (PMN) accumulation and chemokine production within the mouse peritoneal …

Цитокины-это семейство полипептидных молекул, синтезируемых клетками организма
и регулирующих эмбриогенез, ряд нормальных физиологических функций, защитные …

Recently, our laboratory showed that platelets, like leukocytes, roll on activated endothelium
expressing P-selectin, thus suggesting a role for P-selectin in hemostasis (Frenette et al …

Purpura fulminans (PF) is a potentially disabling and life‐threatening disorder characterized
by acute onset of progressive cutaneous hemorrhage and necrosis, and disseminated …

In an attempt to understand the regulatory mechanisms governing passage of neutrophils
from the vascular bed to the interstitial tissue, we analyzed the effect of the pleiotropic …

Acute inflammation constitutes the body's principal mode of defense against infection and
other harmful agents, and neutrophils are the primary effector cells in this process. When …

We find a strong synergism between tumor necrosis factor (TNF) and bacteria or their
products. Endotoxin-" free" recombinant TNF, even at very high doses (160 micrograms), did …