Recent developments in chemical reactivity of N, N-dimethylenamino ketones as synthons for various heterocycles

HM Gaber, MC Bagley, ZA Muhammad, SM Gomha - RSC advances, 2017 - pubs.rsc.org
The current review presents recent progress in the utility of N, N-dimethyl enaminones as
building blocks for a diverse range of acyclic, carbocyclic, five-and six-membered …

Recent Synthetic Approaches to N, N-Dimethyl-β-Ketoenamines

HM Gaber, ZA Muhammad, SM Gomha… - Current Organic …, 2017 - ingentaconnect.com
Background: N, N-dimethyl-β-ketoenamines have proven to be of biological interest and
provide an access to new class of biologically active heterocyclic compounds for biomedical …

New 2-aminobenzothiazole derivatives: Design, synthesis, anti-inflammatory and ulcerogenicity evaluation

SS Awaad, MO Sarhan, WR Mahmoud, T Nasr… - Journal of Molecular …, 2023 - Elsevier
Two series of twenty diversely substituted benzothiazole amides were designed and
synthesized aiming to obtain derivatives with potential anti-inflammatory activity and …

Design and synthesis of novel tranilast analogs: Docking, antiproliferative evaluation and in-silico screening of TGFβR1 inhibitors

MMF Ismail, HSA El-Zahabi, RS Ibrahim… - Bioorganic …, 2020 - Elsevier
The discovery of the antiproliferative potential of tranilast prompted additional studies
directed at understanding the mechanisms of tranilast action. Its inhibitory effect on cell …

Green technologies in organic synthesis: Self-condensation of enamines, enaminones and enaminoesters under microwave irradiation in ionic liquid

KM Al-Zaydi, LM Nhari, RM Borik… - Green Chemistry Letters …, 2010 - Taylor & Francis
Utilizing green technologies as microwave (MW) irradiation and ionic liquids (ILs), we could
produce 1, 3, 5-trisubstituted benzene 3, 7, 9, and 14 by self-condensation of enamines 1 …

[PDF][PDF] Synthesis, anti-bronchoconstrictive, and antibacterial activities of some new 8-substituted-1, 3-dimethylxanthine derivatives

WA Elgaher, AM Hayallah, OIA Salem… - Bulletin of …, 2009 - bpsa.journals.ekb.eg
Methylxanthines especially theophylline have been recognizedas potent bronchodilators for
the relief of acute asthma for over 50years. Recently, it was found that bacterial infection has …

An eco-friendly preparation of 2-iminothiazolidin-4-ones derivatives

G Meng, M Zheng, M Dong, Q Qu - Organic Preparations and …, 2012 - Taylor & Francis
Functionalized 2-thiazolidin-4-ones are important heterocyclic compounds owing to their
biological activities, 1, 2 such as anti-tuberculosis, 3 anti-convulsant, 4 fungistatic, 5 …

Chemistry of Heterocyclic Five and Six Membered Enamino Nitriles and Enamino Esters

MS Moustafa, SM Al-Mousawi… - Mini Reviews in …, 2018 - ingentaconnect.com
Progress in the chemistry of cyclic enamino-nitriles based on the advanced synthetic
methodologies is reported. Due to the recent accomplishment, it becomes possible to …

Синтез, властивості та антиоксидантна активність ряду 5-арил/алкіларил/гетариламінометиленпохідних 2-тіоксо-4-тіазолідинону

АМ Добровольська - 2024 - evnuir.vnu.edu.ua
Похідні 4-тіазолідинону є предметом інтенсивних досліджень в останні десятиліття.
Проте більшість досліджень присвячено вивченню синтезу та фармакологічних …

[HTML][HTML] A study of the reaction of 2-thiazolin-4-ones with some electrophiles under microwave irradiation versus conventional condition

KM Al-Zaydi - Journal of Saudi Chemical Society, 2010 - Elsevier
Coupling of 5-dimethylaminomethylene-3-methyl-2-(pyridine-2-ylimino)-thiazolidin-4-one (3)
with diazotized methyl anthranilate afforded the 3-methyl-5-(2 …