Peeling the onion: how complex is the artemisinin resistance genetic trait of malaria parasites?

M Kucharski, S Nayak, M Gendrot, AM Dondorp… - Trends in …, 2024 - cell.com
The genetics of Plasmodium as an intracellular, mostly haploid, sexually reproducing,
eukaryotic organism with a complex life cycle, presents unprecedented challenges in …

[HTML][HTML] Dihydroartemisinin–Piperaquine Combination in the Treatment of Uncomplicated Plasmodium falciparum Malaria: Update on Clinical Failures in Africa and …

O Delandre, B Pradines, E Javelle - Journal of Clinical Medicine, 2024 - mdpi.com
Dihydroartemisinin (or artenimol)–piperaquine is one of the six artemisinin-based
combination therapies recommended in uncomplicated malaria treatment. However …

Molecular Surveillance of Artemisinin-Resistant Plasmodium falciparum Parasites in Mining Areas of the Roraima Indigenous Territory in Brazil

J de Aguiar-Barros, F Granja… - International Journal of …, 2024 - mdpi.com
Multidrug-and artemisinin-resistant (ART-R) Plasmodium falciparum (Pf) parasites represent
a challenge for malaria elimination worldwide. Molecular monitoring in the Kelch domain …