We develop an approach to find an energy-optimal stimulus that entrains an ensemble of uncertain, uncoupled limit cycle oscillators. Furthermore, when entrainment occurs, the …
Y Hasegawa, M Arita - Journal of The Royal Society …, 2013 - royalsocietypublishing.org
Biological oscillators coordinate individual cellular components so that they function coherently and collectively. They are typically composed of multiple feedback loops, and …
The study of populations of pulse-coupled firing oscillators is a general and simple paradigm to investigate a wealth of natural phenomena, including the collective behaviors of neurons …
Oscillators---whose steady-state behavior is periodic rather than constant---are observed in every field of science. While they have been studied for a long time as closed systems, they …
P Sacré, R Sepulchre - A Systems Theoretic Approach to Systems and …, 2014 - Springer
Sensitivity analysis is a classical and fundamental tool to evaluate the role of a given parameter in a given system characteristic. Because the phase response curve is a …
To characterize the behavior and robustness of cellular circuits is a major challenge for Systems Biology. Many of the published methods that address this question quantify the …