Manipulation and motion of organelles and single molecules in living cells

K Norregaard, R Metzler, CM Ritter… - Chemical …, 2017 - ACS Publications
The biomolecule is among the most important building blocks of biological systems, and a
full understanding of its function forms the scaffold for describing the mechanisms of higher …

[HTML][HTML] Non-Brownian diffusion in lipid membranes: Experiments and simulations

R Metzler, JH Jeon, AG Cherstvy - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
The dynamics of constituents and the surface response of cellular membranes—also in
connection to the binding of various particles and macromolecules to the membrane—are …

Brownian yet non-Gaussian diffusion: from superstatistics to subordination of diffusing diffusivities

AV Chechkin, F Seno, R Metzler, IM Sokolov - Physical Review X, 2017 - APS
A growing number of biological, soft, and active matter systems are observed to exhibit
normal diffusive dynamics with a linear growth of the mean-squared displacement, yet with a …

Bacterial hopping and trapping in porous media

T Bhattacharjee, SS Datta - Nature communications, 2019 - nature.com
Diverse processes—eg bioremediation, biofertilization, and microbial drug delivery—rely on
bacterial migration in disordered, three-dimensional (3D) porous media. However, how pore …

Protein crowding in lipid bilayers gives rise to non-Gaussian anomalous lateral diffusion of phospholipids and proteins

JH Jeon, M Javanainen, H Martinez-Seara, R Metzler… - Physical Review X, 2016 - APS
Biomembranes are exceptionally crowded with proteins with typical protein-to-lipid ratios
being around 1∶ 50− 1∶ 100. Protein crowding has a decisive role in lateral membrane …

Anomalous diffusion of phospholipids and cholesterols in a lipid bilayer and its origins

JH Jeon, HMS Monne, M Javanainen, R Metzler - Physical review letters, 2012 - APS
Combining extensive molecular dynamics simulations of lipid bilayer systems of varying
chemical compositions with single-trajectory analyses, we systematically elucidate the …

Anomalous diffusion and power-law relaxation of the time averaged mean squared displacement in worm-like micellar solutions

JH Jeon, N Leijnse, LB Oddershede… - New Journal of …, 2013 - iopscience.iop.org
We report the results of single tracer particle tracking by optical tweezers and video
microscopy in micellar solutions. From careful analysis in terms of different stochastic …

Fractional Brownian motion with random diffusivity: emerging residual nonergodicity below the correlation time

W Wang, AG Cherstvy, AV Chechkin… - Journal of Physics A …, 2020 - iopscience.iop.org
Numerous examples for a priori unexpected non-Gaussian behaviour for normal and
anomalous diffusion have recently been reported in single-particle tracking experiments …

Aging renewal theory and application to random walks

JHP Schulz, E Barkai, R Metzler - Physical Review X, 2014 - APS
We discuss a renewal process in which successive events are separated by scale-free
waiting time periods. Among other ubiquitous long-time properties, this process exhibits …

Anomalous and normal diffusion of proteins and lipids in crowded lipid membranes

M Javanainen, H Hammaren, L Monticelli… - Faraday …, 2013 - pubs.rsc.org
Lateral diffusion plays a crucial role in numerous processes that take place in cell
membranes, yet it is quite poorly understood in native membranes characterized by, eg …