OCT4 supports extended LIF-independent self-renewal and maintenance of transcriptional and epigenetic networks in embryonic stem cells

R He, B Xhabija, B Al-Qanber, BL Kidder - Scientific Reports, 2017 - nature.com
Embryonic stem (ES) cell pluripotency is governed by OCT4-centric transcriptional networks.
Conventional ES cells can be derived and maintained in vitro with media containing the …

Identification of H4K20me3-and H3K4me3-associated RNAs using CARIP-Seq expands the transcriptional and epigenetic networks of embryonic stem cells

JT Kurup, BL Kidder - Journal of Biological Chemistry, 2018 - ASBMB
RNA has been shown to interact with various proteins to regulate chromatin dynamics and
gene expression. However, it is unknown whether RNAs associate with epigenetic marks …

Activators and repressors: A balancing act for X-inactivation

L Goodrich, B Panning, KN Leung - Seminars in Cell & Developmental …, 2016 - Elsevier
In early female embryos X-chromosome inactivation occurs concomitant with up regulation
of the non-coding RNA, Xist, on the future inactive X-chromosome. Up regulation of Xist and …

DNA methylation is correlated with pluripotency of stem cells

R Wang, T Li - Current Stem Cell Research & Therapy, 2017 - ingentaconnect.com
Background: Pluripotency of stem cells is an important scientific issue and is attracting great
interest for the broader community, especially for regenerative medicine field. Pluripotent …

Culture of haploid blastocysts in FGF4 favors the derivation of epiblast stem cells with a primed epigenetic and transcriptional landscape

R He, BL Kidder - Scientific Reports, 2018 - nature.com
Pluripotent stem cells within the inner cell mass and epiblast of mammalian embryos have
the capacity to form all lineages in the adult organism, while multipotent trophoblast stem …

[PDF][PDF] Mutational Analysis of Xist and the X-inactivation Center

L Goodrich - 2019 - escholarship.org
In placental mammals, dosage compensation of the sex chromosomes isachieved through
inactivation of one X chromosome in female cells. This Xchromosome inactivation (XCI) …

[PDF][PDF] Jiji T. Kurup1-2, Benjamin L. Kidder1-2

BL Kidder - researchgate.net
ABSTRACT RNA has been shown to interact with various proteins to regulate chromatin
dynamics and gene expression. However, it is unknown whether RNAs associate with …