[HTML][HTML] Multifunctional regulatory protein connective tissue growth factor (CTGF): A potential therapeutic target for diverse diseases
M Fu, D Peng, T Lan, Y Wei, X Wei - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Connective tissue growth factor (CTGF), a multifunctional protein of the CCN family,
regulates cell proliferation, differentiation, adhesion, and a variety of other biological …
regulates cell proliferation, differentiation, adhesion, and a variety of other biological …
CCN proteins: opportunities for clinical studies—a personal perspective
H Yeger - Journal of Cell Communication and Signaling, 2023 - Springer
The diverse members of the CCN family now designated as CCN1 (CYR61), CCN2 (CTGF),
CCN3 (NOV), CCN4 (WISP1), CCN5 (WISP2), CCN6 (WISP3) are a conserved matricellular …
CCN3 (NOV), CCN4 (WISP1), CCN5 (WISP2), CCN6 (WISP3) are a conserved matricellular …
Structural insights into regulation of CCN protein activities and functions
VT Monsen, H Attramadal - Journal of cell communication and signaling, 2023 - Springer
CCN proteins play important functions during development, in repair mechanisms following
tissue injury, as well as in pathophysiologic mechanisms of metastasis of cancer. CCNs are …
tissue injury, as well as in pathophysiologic mechanisms of metastasis of cancer. CCNs are …
An" R‐spondin code" for multimodal signaling ON‐OFF states
C Niehrs, C Seidl, H Lee - BioEssays, 2024 - Wiley Online Library
R‐spondins (RSPOs) are a family of secreted proteins and stem cell growth factors that are
potent co‐activators of Wnt signaling. Recently, RSPO2 and RSPO3 were shown to be …
potent co‐activators of Wnt signaling. Recently, RSPO2 and RSPO3 were shown to be …
The carboxyl-terminal TSP1-homology domain is the biologically active effector peptide of matricellular protein CCN5 that counteracts profibrotic CCN2
S Zolfaghari, OJ Kaasbøll, VT Monsen, B Sredic… - Journal of Biological …, 2023 - ASBMB
Cellular Communication Network (CCN) proteins have multimodular structures important for
their roles in cellular responses associated with organ development and tissue homeostasis …
their roles in cellular responses associated with organ development and tissue homeostasis …
Connective tissue growth factor-targeting DNA aptamer suppresses pannus formation as diagnostics and therapeutics for rheumatoid arthritis
G Wu, C Liu, B Cao, Z Cao, H Zhai, B Liu, S Jin… - Frontiers in …, 2022 - frontiersin.org
Connective tissue growth factor (CTGF) has been recently acknowledged as an ideal
biomarker in the early disease course, participating in the pathogenesis of pannus formation …
biomarker in the early disease course, participating in the pathogenesis of pannus formation …
The structure and proteomic analysis of byssus in Pteria penguin: Insights into byssus evolution and formation
Y Chen, H Chen, C Han, H Ou, X Zhan - Journal of Proteomics, 2024 - Elsevier
Byssus is a unique external structure in sessile bivalves and is critical for settlement and
metamorphosis. However, little is known about the stout byssus in Pteria penguin. We …
metamorphosis. However, little is known about the stout byssus in Pteria penguin. We …
The byssal-producing glands and proteins of the silverlip pearl oyster Pinctada maxima (Jameson, 1901)
Pinctada maxima are most well known for their production of high-quality natural pearls.
They also generate another natural material, the byssus, an adhesive thread critical for …
They also generate another natural material, the byssus, an adhesive thread critical for …
Investigations on regulation, signaling properties and functions of CCN5
S Zolfaghari - 2024 - duo.uio.no
Our research group has previously shown that CCN2 is secreted as a preproprotein that
requires proteolytic activation in order to release the biologically active entity. CCN5 is a …
requires proteolytic activation in order to release the biologically active entity. CCN5 is a …