[HTML][HTML] Magnetic iron oxide nanoparticles for brain imaging and drug delivery
Central nervous system (CNS) disorders affect as many as 1.5 billion people globally. The
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …
Near-infrared fluorescent probes as imaging and theranostic modalities for amyloid-beta and tau aggregates in Alzheimer's disease
A person suspected of having Alzheimer's disease (AD) is clinically diagnosed for the
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …
Recent advances in the treatment of Alzheimer's disease using nanoparticle-based drug delivery systems
P Poudel, S Park - Pharmaceutics, 2022 - mdpi.com
Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disorder.
Most existing treatments only provide symptomatic solutions. Here, we introduce currently …
Most existing treatments only provide symptomatic solutions. Here, we introduce currently …
Advances in nanomedicines for diagnosis of central nervous system disorders
In spite of a great improvement in medical health services and an increase in lifespan, we
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …
Application of iron oxide nanoparticles in the diagnosis and treatment of neurodegenerative diseases with emphasis on Alzheimer's disease
S Luo, C Ma, MQ Zhu, WN Ju, Y Yang… - Frontiers in cellular …, 2020 - frontiersin.org
Neurodegenerative diseases are characterized by chronic progressive degeneration of the
structure and function of the nervous system, which brings an enormous burden on patients …
structure and function of the nervous system, which brings an enormous burden on patients …
Nanomedicine-based immunotherapy for alzheimer's disease
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease caused by the
deposition of amyloid β (Aβ) fibrils forming extracellular plaques and the development of …
deposition of amyloid β (Aβ) fibrils forming extracellular plaques and the development of …
Nanotechnological strategies for nerve growth factor delivery: Therapeutic implications in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
amyloid-β peptide misfolding and aggregation. Neurotrophic factors, such as nerve growth …
amyloid-β peptide misfolding and aggregation. Neurotrophic factors, such as nerve growth …
Machine learning assisted-nanomedicine using magnetic nanoparticles for central nervous system diseases
Magnetic nanoparticles possess unique properties distinct from other types of nanoparticles
developed for biomedical applications. Their unique magnetic properties and …
developed for biomedical applications. Their unique magnetic properties and …
Molecular tools to detect alloforms of Aβ and Tau: Implications for multiplexing and multimodal diagnosis of Alzheimer's disease
The advancements in the field of imaging and diagnostics have been benefitted by the
concurrent expansion of molecular probes space to monitor the diverse biological targets …
concurrent expansion of molecular probes space to monitor the diverse biological targets …
Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication
A Munke, J Persson, T Weiffert… - Proceedings of the …, 2017 - National Acad Sciences
The aggregation of the amyloid β peptide (Aβ) into amyloid fibrils is a defining characteristic
of Alzheimer's disease. Because of the complexity of this aggregation process, effective …
of Alzheimer's disease. Because of the complexity of this aggregation process, effective …