Anti-melanoma differentiation–associated gene 5 (MDA5) dermatomyositis: a concise review with an emphasis on distinctive clinical features

DJB Kurtzman, RA Vleugels - Journal of the American Academy of …, 2018 - Elsevier
Melanoma differentiation–associated gene 5 (MDA5) is a recently described autoantigen
target in a subset of patients with dermatomyositis. Anti-MDA5 dermatomyositis is …

Recommendations for the treatment of anti-melanoma differentiation-associated gene 5-positive dermatomyositis-associated rapidly progressive interstitial lung …

F Romero-Bueno, PD Del Campo… - Seminars in arthritis and …, 2020 - Elsevier
Objectives The study aimed to develop evidence-based recommendations for the treatment
of rapidly progressive interstitial lung disease (RPILD) associated with the anti-Melanoma …

Describing and expanding the clinical phenotype of anti-MDA5-associated rapidly progressive interstitial lung disease: case series of nine Canadian patients and …

S Hoa, Y Troyanov, MJ Fritzler, IN Targoff… - Scandinavian Journal …, 2018 - Taylor & Francis
Objective: To describe and expand the phenotype of anti-MDA5-associated rapidly
progressive interstitial lung disease (MDA5-RPILD) in Canadian patients. Method: All …

MDA5 expression is associated with TGF-β-induced fibrosis: potential mechanism of interstitial lung disease in anti-MDA5 dermatomyositis

N Shen, X Zhou, X Jin, C Lu, X Hu, Y Zhang… - …, 2023 - academic.oup.com
Objectives This study aimed to investigate the high-resolution CT (HRCT) characteristics of
anti-melanoma differentiation-associated gene 5 (MDA5) antibody positive dermatomyositis …

Recent advances in connective tissue disease related interstitial lung disease

A Suzuki, Y Kondoh, A Fischer - Expert Review of Respiratory …, 2017 - Taylor & Francis
Introduction: Interstitial lung disease (ILD) is a common manifestation of connective tissue
disease (CTD). Although the majority of patients with CTD-ILD are stable or slowly …

Mitochondrial morphology and MAVS‐IFN1 signaling pathway in muscles of anti‐MDA5 dermatomyositis

Y Jiang, Y Liu, Y Zhao, Y Zheng, M Yu… - Annals of Clinical …, 2021 - Wiley Online Library
Objective This study aimed to investigate mitochondrial changes and the mitochondrial
antiviral‐signaling protein (MAVS)‐type I interferon (IFN1) signaling pathway in the muscles …

Multidisciplinary Approach to the Diagnosis of Idiopathic Interstitial Pneumonias: Focus on the Pathologist's Key Role

S Lucà, F Pagliuca, F Perrotta, A Ronchi… - International Journal of …, 2024 - mdpi.com
Idiopathic Interstitial Pneumonias (IIPs) are a heterogeneous group of the broader category
of Interstitial Lung Diseases (ILDs), pathologically characterized by the distortion of lung …

[PDF][PDF] One year in review 2017: idiopathic inflammatory myopathies

S Barsotti, C Bruni, L Cometi, V Valentini… - Clin Exp …, 2017 - researchgate.net
Every year new concepts about pathogenesis, serology, diagnosis and treatment in
inflammatory myopathies (IIMs) have been provided. The purpose of this manuscript is to …

Pathology of idiopathic interstitial pneumonias

Y Zaizen, J Fukuoka - Surgical pathology clinics, 2020 - surgpath.theclinics.com
This review discusses diagnostic pathology in idiopathic interstitial pneumonias (IIPs).
Accurate understanding of basic structure of lung lobules is critical because the location of …

[HTML][HTML] Idiopathic Inflammatory Myopathies-Associated Interstitial Lung Disease in Adults

M Moda, T Yanagihara, R Nakashima… - Tuberculosis and …, 2024 - pmc.ncbi.nlm.nih.gov
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of autoimmune
diseases characterized by muscle involvement and various extramuscular manifestations …