Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer's disease

CD Morrone, R Raghuraman, SA Hussaini… - Molecular …, 2023 - Springer
Failed proteostasis is a well-documented feature of Alzheimer's disease, particularly,
reduced protein degradation and clearance. However, the contribution of failed proteostasis …

[HTML][HTML] Impact of sleep disturbances on neurodegeneration: Insight from studies in animal models

JE Owen, SC Veasey - Neurobiology of disease, 2020 - Elsevier
Chronic short sleep or extended wake periods are commonly observed in most
industrialized countries. Previously neurobehavioral impairment following sleep loss was …

The anti-apoptotic, antioxidant and anti-inflammatory effects of curcumin on acrylamide-induced neurotoxicity in rats

J Guo, X Cao, X Hu, S Li, J Wang - BMC Pharmacology and Toxicology, 2020 - Springer
Background Acrylamide (ACR) formed during heating of tobacco and carbohydrate-rich food
as well as widely applied in industries has been known as a well-established neurotoxic …

[HTML][HTML] A brief period of sleep deprivation causes spine loss in the dentate gyrus of mice

F Raven, P Meerlo, EA Van der Zee, T Abel… - … of Learning and …, 2019 - Elsevier
Sleep and sleep loss have a profound impact on hippocampal function, leading to memory
impairments. Modifications in the strength of synaptic connections directly influences …

Neonatal curcumin treatment restores hippocampal neurogenesis and improves autism-related behaviors in a mouse model of autism

H Zhong, R Xiao, R Ruan, H Liu, X Li, Y Cai, J Zhao… - …, 2020 - Springer
Abstract Rationale Autism spectrum disorders (ASDs) are highly prevalent
neurodevelopmental disorders characterized by deficits in social communication and …

Effect of chronic sleep deprivation and sleep recovery on hippocampal CA3 neurons, spatial memory and anxiety-like behavior in rats

S Konakanchi, V Raavi, HK Ml, V Shankar - Neurobiology of Learning and …, 2022 - Elsevier
Sleep deprivation-induced degenerative changes in the brain lead to the impairment of
memory, anxiety, and quality of life. Several studies have reported the effects of sleep …

Gut microbiota: Candidates for a novel strategy for ameliorating sleep disorders

L Li, T Liang, T Jiang, Y Li, L Yang, L Wu… - Critical Reviews in …, 2024 - Taylor & Francis
The aim of this review was to evaluate the feasibility of treating sleep disorders using novel
gut microbiota intervention strategies. Multiple factors can cause sleep disorders, including …

[HTML][HTML] REM sleep deprivation induced by the modified multi-platform method has detrimental effects on memory: A systematic review and meta-analysis

H Diao, Y Li, W Sun, J Zhang, M Wang, Y Chen… - Behavioural Brain …, 2023 - Elsevier
The modified multi-platform method (MMPM) is used to induce animal models of paradoxical
sleep deprivation and impairs memory in rodents. However, variations in MMPM protocols …

Sleep, neuronal hyperexcitability, inflammation and neurodegeneration: Does early chronic short sleep trigger and is it the key to overcoming Alzheimer's disease?

A Ahnaou, W Drinkenburg - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Evidence links neuroinflammation to Alzheimer's disease (AD); however, its exact
contribution to the onset and progression of the disease is poorly understood. Symptoms of …

Recent advances in the aetiology of recurrent aphthous stomatitis (RAS)

Z Wang, H Cao, J Xiong, Y Lu, Y Deng… - Postgraduate …, 2022 - academic.oup.com
Recurrent aphthous stomatitis (RAS) is the most common disease of oral mucosa, which
almost attacks each individual once in their lifespan. Although plenty of factors have been …