The sublingual and buccal routes of administration have significant advantages for both
local and systemic drug delivery. They have shown to be an effective alternative to the …

The importance of drug dosing time in pharmacokinetics, pharmacodynamics, and toxicity is
receiving increasing attention from the scientific community. In spite of mounting evidence …

Zaleplon (ZP) is a sedative and hypnotic drug used for the treatment of insomnia. Despite its
potent anticonvulsant activity, ZP is not commonly used for the treatment of convulsion since …

Aging causes progressive deterioration of daily rhythms in behavioral and metabolic
processes and disruption in the regular sleep-wake cycle. Circadian disruption is directly …

The purpose of this study is to develop solid self-nanoemulsifying drug delivery systems (S-
SNEDDS) for oral bioavailability enhancement of Clopidogrel (CLP). CLP is an anti-platelet …

Owing to the dysphagia and gastroparesis in patients concomitant with Parkinson's disease
(PD), oral amantadine (AMT) medications are susceptible to poor bioavailability and clinical …

Introduction Of the various transmucosal routes which are being considered for extended
and controlled drug delivery, buccal route is superior to other methods owing to high …

Our investigation is regarding the preparation and characterization of Curcumin-loaded
novasomes (CLN) using thin film hydration technique. Curcumin is spotlighted for cancer …

This study aimed to prepare a combined self-nanoemulsifying and self-assembled cubic
nanoparticles (SNE/SAC) lyophilized tablet eliciting biphasic release pattern escorted with …

Insomnia remains a common clinical challenge for which a wide variety of substances and
medications have been tried by individuals and recommended by health professionals. This …