Inflammation in anxiety

S Salim, G Chugh, M Asghar - Advances in protein chemistry and structural …, 2012 - Elsevier
The idea of the existence of an interaction between the immune system and the central
nervous system (CNS) has prompted extensive research interest into the subject of “ …

The NPY system in stress, anxiety and depression

M Heilig - Neuropeptides, 2004 - Elsevier
NPY antagonizes behavioral consequences of stress through actions within the brain.
Behavioral anti-stress actions of NPY are noteworthy in that (1) their magnitude surpasses …

Depression, anxiety-like behavior and memory impairment are associated with increased oxidative stress and inflammation in a rat model of social stress

G Patki, N Solanki, F Atrooz, F Allam, S Salim - Brain research, 2013 - Elsevier
In the present study, we have examined the behavioral and biochemical effect of induction of
psychological stress using a modified version of the resident-intruder model for social stress …

Neurobiology of addiction: An integrative review

A Goodman - Biochemical pharmacology, 2008 - Elsevier
Evidence that psychoactive substance use disorders, bulimia nervosa, pathological
gambling, and sexual addiction share an underlying biopsychological process is …

Brain chromatin remodeling: a novel mechanism of alcoholism

SC Pandey, R Ugale, H Zhang, L Tang… - Journal of …, 2008 - Soc Neuroscience
The treatment of alcoholism requires the proper management of ethanol withdrawal
symptoms, such as anxiety, to prevent further alcohol use and abuse. In this study, we …

Epigenetic basis of the dark side of alcohol addiction

SC Pandey, EJ Kyzar, H Zhang - Neuropharmacology, 2017 - Elsevier
Alcoholism is a complex brain disease characterized by three distinct stages of the addiction
cycle that manifest as neuroadaptive changes in the brain. One such stage of the addiction …

Stress, alcohol and drug interaction: an update of human research

M Uhart, GS Wand - Addiction biology, 2009 - Wiley Online Library
ABSTRACT A challenging question that continues unanswered in the field of addiction is
why some individuals are more vulnerable to substance use disorders than others …

Omega-3 fatty acid deficiency during brain maturation reduces neuronal and behavioral plasticity in adulthood

HS Bhatia, R Agrawal, S Sharma, YX Huo, Z Ying… - PloS one, 2011 - journals.plos.org
Omega-3-fatty acid DHA is a structural component of brain plasma membranes, thereby
crucial for neuronal signaling; however, the brain is inefficient at synthesizing DHA. We have …

Lifestyle, pregnancy and epigenetic effects

S Barua, MA Junaid - Epigenomics, 2015 - Taylor & Francis
Rapidly growing evidences link maternal lifestyle and prenatal factors with serious health
consequences and diseases later in life. Extensive epidemiological studies have identified a …

Aberrant histone deacetylase2–mediated histone modifications and synaptic plasticity in the amygdala predisposes to anxiety and alcoholism

S Moonat, AJ Sakharkar, H Zhang, L Tang… - Biological …, 2013 - Elsevier
BACKGROUND: Epigenetic mechanisms have been implicated in psychiatric disorders,
including alcohol dependence. However, the epigenetic basis and role of specific histone …