Establishing neural crest identity: a gene regulatory recipe
M Simões-Costa, ME Bronner - Development, 2015 - journals.biologists.com
The neural crest is a stem/progenitor cell population that contributes to a wide variety of
derivatives, including sensory and autonomic ganglia, cartilage and bone of the face and …
derivatives, including sensory and autonomic ganglia, cartilage and bone of the face and …
A gene regulatory network orchestrates neural crest formation
T Sauka-Spengler, M Bronner-Fraser - Nature reviews Molecular cell …, 2008 - nature.com
The neural crest is a multipotent, migratory cell population that is unique to vertebrate
embryos and gives rise to many derivatives, ranging from the peripheral nervous system to …
embryos and gives rise to many derivatives, ranging from the peripheral nervous system to …
A modular platform for differentiation of human PSCs into all major ectodermal lineages
Directing the fate of human pluripotent stem cells (hPSCs) into different lineages requires
variable starting conditions and components with undefined activities, introducing …
variable starting conditions and components with undefined activities, introducing …
The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it
ED Hay - Developmental dynamics: an official publication of …, 2005 - Wiley Online Library
This review centers on the role of the mesenchymal cell in development. The creation of this
cell is a remarkable process, one where a tightly knit, impervious epithelium suddenly …
cell is a remarkable process, one where a tightly knit, impervious epithelium suddenly …
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature
KS Hoek, NC Schlegel, P Brafford, A Sucker… - Pigment cell …, 2006 - Wiley Online Library
The molecular biology of metastatic potential in melanoma has been studied many times
previously and changes in the expression of many genes have been linked to metastatic …
previously and changes in the expression of many genes have been linked to metastatic …
Neural crest development is regulated by the transcription factor Sox9
The neural crest is a transient migratory population of stem cells derived from the dorsal
neural folds at the border between neural and non-neural ectoderm. Following induction …
neural folds at the border between neural and non-neural ectoderm. Following induction …
The AP-2 family of transcription factors
The AP-2 family of transcription factors consists of five different proteins in humans and mice:
AP-2α, AP-2β, AP-2γ, AP-2δ and AP-2ε. Frogs and fish have known orthologs of some but …
AP-2α, AP-2β, AP-2γ, AP-2δ and AP-2ε. Frogs and fish have known orthologs of some but …
Regulatory logic underlying diversification of the neural crest
ML Martik, ME Bronner - Trends in Genetics, 2017 - cell.com
The neural crest is a transient, multipotent population of cells that arises at the border of the
developing nervous system. After closure of the neural tube, these cells undergo an …
developing nervous system. After closure of the neural tube, these cells undergo an …
Gene-regulatory interactions in neural crest evolution and development
D Meulemans, M Bronner-Fraser - Developmental cell, 2004 - cell.com
In this review, we outline the gene-regulatory interactions driving neural crest development
and compare these to a hypothetical network operating in the embryonic ectoderm of the …
and compare these to a hypothetical network operating in the embryonic ectoderm of the …
A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development
Understanding how developmental systems evolve after genome amplification is important
for discerning the origins of vertebrate novelties, including neural crest, placodes, cartilage …
for discerning the origins of vertebrate novelties, including neural crest, placodes, cartilage …