International guidelines for management of metastatic breast cancer: can metastatic breast cancer be cured?

O Pagani, E Senkus, W Wood… - Journal of the …, 2010 - academic.oup.com
A distinctive subset of metastatic breast cancer (MBC) is oligometastatic disease, which is
characterized by single or few detectable metastatic lesions. The existing treatment …

Breast surgery in stage IV breast cancer: impact of staging and patient selection on overall survival

AC Bafford, HJ Burstein, CR Barkley, BL Smith… - Breast cancer research …, 2009 - Springer
Purpose Retrospective analyses suggest patients with stage IV breast cancer who undergo
breast surgery have improved survival. We sought to determine whether surgery and other …

Early local therapy for the primary site in de novo stage IV breast cancer: results of a randomized clinical trial (E2108)

SA Khan, F Zhao, LJ Goldstein, D Cella… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Distant metastases are present in 6% or more of patients with newly diagnosed
breast cancer. In this context, locoregional therapy for the intact primary tumor has been …

Randomized trial comparing resection of primary tumor with no surgery in stage IV breast cancer at presentation: protocol MF07-01

A Soran, V Ozmen, S Ozbas, H Karanlik… - Annals of surgical …, 2018 - Springer
Background The MF07-01 trial is a multicenter, phase III, randomized, controlled study
comparing locoregional treatment (LRT) followed by systemic therapy (ST) with ST alone for …

Locoregional treatment versus no treatment of the primary tumour in metastatic breast cancer: an open-label randomised controlled trial

R Badwe, R Hawaldar, N Nair, R Kaushik… - The lancet …, 2015 - thelancet.com
Background The role of locoregional treatment in women with metastatic breast cancer at
first presentation is unclear. Preclinical evidence suggests that such treatment might help the …

Impact of breast surgery in primary metastasized breast cancer: outcomes of the prospective randomized phase III ABCSG-28 POSYTIVE trial

F Fitzal, V Bjelic-Radisic, M Knauer, G Steger… - Annals of …, 2019 - journals.lww.com
Background: Conflicting evidence exists regarding the value of surgical resection of the
primary in stage IV breast cancer patients. Objective: The prospective randomized phase III …

Primary surgery with systemic therapy in patients with de novo stage IV breast cancer: 10-year follow-up; protocol MF07-01 randomized clinical trial

A Soran, V Ozmen, S Ozbas, H Karanlik… - Journal of the American …, 2021 - Elsevier
Background The aim of this randomized clinical trial was to evaluate the overall survival
(OS) data of patients diagnosed with de novo stage IV breast cancer (BC) who received …

Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey

LG Hemkens, DG Contopoulos-Ioannidis… - bmj, 2016 - bmj.com
Objective To assess differences in estimated treatment effects for mortality between
observational studies with routinely collected health data (RCD; that are published before …

Initial surgery and survival in stage IV breast cancer in the United States, 1988-2011

A Thomas, SA Khan, EA Chrischilles… - JAMA …, 2016 - jamanetwork.com
Importance Management of the primary tumor site in patients with metastatic breast cancer
remains controversial. Objective To evaluate the patterns of receipt of initial breast surgery …

Novel models by machine learning to predict prognosis of breast cancer brain metastases

C Li, M Liu, Y Zhang, Y Wang, J Li, S Sun, X Liu… - Journal of translational …, 2023 - Springer
Background Breast cancer brain metastases (BCBM) are the most fatal, with limited survival
in all breast cancer distant metastases. These patients are deemed to be incurable. Thus …