Selective neuromodulation of the vagus nerve

A Fitchett, S Mastitskaya, K Aristovich - Frontiers in neuroscience, 2021 - frontiersin.org
Vagus nerve stimulation (VNS) is an effective technique for the treatment of refractory
epilepsy and shows potential for the treatment of a range of other serious conditions …

Selective vagus nerve stimulation as a therapeutic approach for the treatment of ARDS: a rationale for neuro-immunomodulation in COVID-19 disease

S Mastitskaya, N Thompson, D Holder - Frontiers in neuroscience, 2021 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is the most severe form of acute lung injury. It is
induced by sepsis, aspiration, and pneumonia, including that caused by SARS coronavirus …

[HTML][HTML] Organ-and function-specific anatomical organization of vagal fibers supports fascicular vagus nerve stimulation

N Jayaprakash, W Song, V Toth, A Vardhan, T Levy… - Brain stimulation, 2023 - Elsevier
Vagal fibers travel inside fascicles and form branches to innervate organs and regulate
organ functions. Existing vagus nerve stimulation (VNS) therapies activate vagal fibers non …

Closed-loop vagus nerve stimulation for the treatment of cardiovascular diseases: state of the art and future directions

MM Ottaviani, F Vallone, S Micera… - Frontiers in …, 2022 - frontiersin.org
The autonomic nervous system exerts a fine beat-to-beat regulation of cardiovascular
functions and is consequently involved in the onset and progression of many cardiovascular …

Organotopic organization of the porcine mid-cervical vagus nerve

N Thompson, E Ravagli, S Mastitskaya… - Frontiers in …, 2023 - frontiersin.org
Introduction Despite detailed characterization of fascicular organization of somatic nerves,
the functional anatomy of fascicles evident in human and large mammal cervical vagus …

Imaging fascicular organization of rat sciatic nerves with fast neural electrical impedance tomography

E Ravagli, S Mastitskaya, N Thompson… - Nature …, 2020 - nature.com
Imaging compound action potentials (CAPs) in peripheral nerves could help avoid side
effects in neuromodulation by selective stimulation of identified fascicles. Existing methods …

Three-dimensional engineered peripheral nerve: toward a new era of patient-specific nerve repair solutions

OA Selim, S Lakhani, S Midha, A Mosahebi… - … Engineering Part B …, 2022 - liebertpub.com
Reconstruction of peripheral nerve injuries (PNIs) with substance loss remains challenging
because of limited treatment solutions and unsatisfactory patient outcomes. Currently, nerve …

Organ-and function-specific anatomical organization and bioelectronic modulation of the vagus nerve

N Jayaprakash, V Toth, W Song, A Vardhan, T Levy… - BioRxiv, 2022 - biorxiv.org
Afferent and efferent fibers in the vagus nerve travel inside fascicles and form branches to
innervate organs and regulate organ functions. The spatial organization of fibers and …

Simultaneous decoding of cardiovascular and respiratory functional changes from pig intraneural vagus nerve signals

F Vallone, MM Ottaviani, F Dedola… - Journal of neural …, 2021 - iopscience.iop.org
Objective. Bioelectronic medicine is opening new perspectives for the treatment of some
major chronic diseases through the physical modulation of autonomic nervous system …

Blood supply and microcirculation of the peripheral nerve

C Prahm, J Heinzel, J Kolbenschlag - Peripheral nerve tissue engineering …, 2022 - Springer
The aim of this chapter is to comprehensively compile the current body of knowledge
relating to the blood supply and microcirculation of the peripheral nerve. Key findings are …