Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

The diabetogenic effects of pesticides: Evidence based on epidemiological and toxicological studies

Y Wei, L Wang, J Liu - Environmental Pollution, 2023 - Elsevier
While the use of pesticides has improved grain productivity and controlled vector-borne
diseases, the widespread use of pesticides has resulted in ubiquitous environmental …

[HTML][HTML] Adipose tissue and endocrine-disrupting chemicals: does sex matter?

B Le Magueresse-Battistoni - … of environmental research and public health, 2020 - mdpi.com
Obesity and metabolic-related diseases, among which diabetes, are prominent public health
challenges of the 21st century. It is now well acknowledged that pollutants are a part of the …

Stress, sex, and sugar: glucocorticoids and sex-steroid crosstalk in the sex-specific misprogramming of metabolism

D Ruiz, V Padmanabhan… - Journal of the Endocrine …, 2020 - academic.oup.com
Early-life exposures to environmental insults can misprogram development and increase
metabolic disease risk in a sex-dependent manner by mechanisms that remain poorly …

Endocrine disrupting chemicals and metabolic disorders in the liver: What if we also looked at the female side?

B Le Magueresse-Battistoni - Chemosphere, 2021 - Elsevier
Endocrine disrupting chemicals (EDCs) are linked to the worldwide epidemic incidence of
metabolic disorders and fatty liver diseases, which affects quality of life and represents a …

[HTML][HTML] Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies …

L Smith, W Klement, L Dopavogui, F De Bock… - Environment …, 2020 - Elsevier
Background We recently demonstrated that chronic dietary exposure to a mixture of
pesticides at low-doses induced sexually dimorphic obesogenic and diabetogenic effects in …

Wildlife ecotoxicology of plant protection products: knowns and unknowns about the impacts of currently used pesticides on terrestrial vertebrate biodiversity

C Fritsch, P Berny, O Crouzet, S Le Perchec… - … Science and Pollution …, 2024 - Springer
Agricultural practices are a major cause of the current loss of biodiversity. Among postwar
agricultural intensification practices, the use of plant protection products (PPPs) might be …

Arsenic exposure decreases adiposity during high‐fat feeding

CM Carmean, AG Kirkley, M Landeche, H Ye… - …, 2020 - Wiley Online Library
Objective Arsenic is an endocrine‐disrupting chemical associated with diabetes risk.
Increased adiposity is a significant risk factor for diabetes and its comorbidities. Here, the …

Screening of potential oestrogen receptor α agonists in pesticides via in silico, in vitro and in vivo methods

C Shen, K Zhu, J Ruan, J Li, Y Wang, M Zhao… - Environmental …, 2021 - Elsevier
In modern agricultural management, the use of pesticides is indispensable. Due to their
massive use worldwide, pesticides represent a latent risk to both humans and the …

Inappropriately sweet: Environmental endocrine-disrupting chemicals and the diabetes pandemic

MC Schulz, RM Sargis - Advances in Pharmacology, 2021 - Elsevier
Afflicting hundreds of millions of individuals globally, diabetes mellitus is a chronic disorder
of energy metabolism characterized by hyperglycemia and other metabolic derangements …