Early developmental conditioning of later health and disease: physiology or pathophysiology?

MA Hanson, PD Gluckman - Physiological reviews, 2014 - journals.physiology.org
Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

Cardiovascular risk factors in children and young adults born to preeclamptic pregnancies: a systematic review

EF Davis, M Lazdam, AJ Lewandowski, SA Worton… - …, 2012 - publications.aap.org
BACKGROUND AND OBJECTIVE: Preeclampsia is an independent cardiovascular risk
factor for the mother, and recent studies reveal that offspring of affected pregnancies also …

Associations of maternal prepregnancy body mass index and gestational weight gain with adult offspring cardiometabolic risk factors: the Jerusalem Perinatal Family …

H Hochner, Y Friedlander, R Calderon-Margalit… - Circulation, 2012 - Am Heart Assoc
Background—Accumulating evidence demonstrates that both maternal prepregnancy body
mass index (mppBMI) and gestational weight gain (GWG) are associated with adult offspring …

Evaluation of the association between maternal smoking, childhood obesity, and metabolic disorders: a national toxicology program workshop review

M Behl, D Rao, K Aagaard, TL Davidson… - Environmental …, 2013 - ehp.niehs.nih.gov
Background: An emerging literature suggests that environmental chemicals may play a role
in the development of childhood obesity and metabolic disorders, especially when exposure …

Cardiovascular risk factors in offspring of preeclamptic pregnancies—systematic review and meta-analysis

PH Andraweera, ZS Lassi - The Journal of pediatrics, 2019 - Elsevier
Objective To evaluate evidence for increased cardiovascular disease (CVD) risk factors in
children exposed to preeclampsia in utero. Study design PubMed, the Cumulative Index to …

Impact of metabolic hormones secreted in human breast milk on nutritional programming in childhood obesity

PA Badillo-Suárez, M Rodríguez-Cruz… - Journal of mammary …, 2017 - Springer
Obesity is the most common metabolic disease whose prevalence is increasing worldwide.
This condition is considered a serious public health problem due to associated …

Maternal obesity and the developmental programming of hypertension: a role for leptin

PD Taylor, AM Samuelsson, L Poston - Acta physiologica, 2014 - Wiley Online Library
Mother–child cohort studies have established that both pre‐pregnancy body mass index
(BMI) and gestational weight gain are independently associated with cardio‐metabolic risk …

Mechanisms by which maternal obesity programs offspring for obesity: evidence from animal studies

E Zambrano, PW Nathanielsz - Nutrition reviews, 2013 - academic.oup.com
Maternal obesity can profoundly affect offspring phenotype and predisposition to obesity and
metabolic disease. Carefully controlled studies in precocial and altricial mammalian species …

[HTML][HTML] Cardiovascular and metabolic influences of fetal smoke exposure

H Bakker, VWV Jaddoe - European journal of epidemiology, 2011 - Springer
Many epidemiological studies showed associations of low birth weight with cardiovascular
disease, type 2 diabetes and obesity. The associations seem to be consistent and stronger …

Programming by maternal obesity: a pathway to poor cardiometabolic health in the offspring

I Inzani, SE Ozanne - Proceedings of the Nutrition Society, 2022 - cambridge.org
There is an ever increasing prevalence of maternal obesity worldwide such that in many
populations over half of women enter pregnancy either overweight or obese. This review …