Neuroinflammation is a critical degradative condition affecting neurons in the brain.
Progressive neurodegenerative conditions such as Alzheimer's disease and Parkinson's …

Stilbenes are phytoalexins, and their biosynthesis can occur through a natural route
(shikimate precursor) or an alternative route (in microorganism cultures). The latter is a …

Neutrophil extracellular traps (NETs) play a crucial role in breast cancer metastasis.
However, the therapeutic target of NETs in breast cancer metastasis is still unknown. Using …

Mitophagy, the cellular process of selectively eliminating damaged mitochondria, plays a
crucial role in maintaining metabolic balance and preventing insulin resistance, both key …

Cabazitaxel has been approved for the treatment of prostate cancer since 2010. However,
its poor solubility and permeability pitfalls prevent its accumulation at the target site and …

As the quality of life improves, the incidence of diabetes mellitus and its microvascular
complications (DMC) continues to increase, posing a threat to people's health and …

Abstract Type-1 IFN (interferon)-associated innate immune response is increasingly getting
attention in neurodegenerative and metabolic diseases like type 2 diabetes (T2DM) …

Lymphoma is a cancer affecting the lymphatic system that fights infections and diseases. In
addition to surgery, radiotherapy, and chemotherapy, novel approaches have recently been …

Type 2 diabetes mellitus (T2DM) is a persistent metabolic disorder marked by deficiencies in
insulin secretion and/or function, affecting various tissues and organs and leading to …

Abstract Sphingosine-1-phosphate (S1P) is emerging as a crucial sphingolipid modulating
neuroinflammation and cognition. S1P levels in the brain have been found to be decreased …