Normal skeletal muscle functions are affected following trauma, chronic diseases, inherited
neuromuscular disorders, aging, and cachexia, hampering the daily activities and quality of …

The injury of adult skeletal muscle initiates series of well‐coordinated events that lead to the
efficient repair of the damaged tissue. Any disturbances during muscle myolysis or …

Fibrosis occurs in skeletal muscle under various pathophysiological conditions such as
Duchenne muscular dystrophy (DMD), a devastating disease characterized by fiber …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and
lower motoneurons degenerate leading to muscle wasting, paralysis and eventually death …

The regulation of stem cells that maintain and regenerate postnatal tissues depends on
extrinsic signals originating from their microenvironment, commonly referred to as the stem …

In Duchenne muscular dystrophy (DMD) and the mdx mouse model, the absence of the
cytoskeletal protein dystrophin causes defective anchoring of myofibres to the basal lamina …

Transcription of specific skeletal muscle genes requires the expression of the muscle
regulatory factor myogenin. To assess the role of the extracellular matrix (ECM) in skeletal …

Duchenne muscular dystrophy (DMD) is the most common inherited neuromuscular
disease, and is characterized by the lack of dystrophin, muscle wasting, increased …

1 What follows are neuron diagrams, which are a useful way to represent causal structures.
The conventions are as follows. Filled circles doubly represent firing neurons and occurring …

Several skeletal muscle diseases are characterized by fibrosis, the excessive accumulation
of extracellular matrix. Transforming growth factor-β (TGF-β) and connective tissue growth …