Pharmacological properties and molecular mechanisms of thymol: prospects for its therapeutic potential and pharmaceutical development

MF Nagoor Meeran, H Javed, H Al Taee… - Frontiers in …, 2017 - frontiersin.org
Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline
monoterpene phenol. It is one of the most important dietary constituents in thyme species …

Therapeutic application of carvacrol: A comprehensive review

M Imran, M Aslam, SA Alsagaby, F Saeed… - Food science & …, 2022 - Wiley Online Library
Carvacrol is a major natural constituent and is significantly present as an essential oil in
aromatic plants and is well known for its numerous biological activities. Therapeutic …

Cell sources for in vitro human liver cell culture models

K Zeilinger, N Freyer, G Damm… - Experimental …, 2016 - journals.sagepub.com
In vitro liver cell culture models are gaining increasing importance in pharmacological and
toxicological research. The source of cells used is critical for the relevance and the …

Therapeutic potential of plants and plant derived phytochemicals against acetaminophen-induced liver injury

SB Subramanya, B Venkataraman… - International journal of …, 2018 - mdpi.com
Acetaminophen (APAP), which is also known as paracetamol or N-acetyl-p-aminophenol is
a safe and potent drug for fever, pain and inflammation when used at its normal therapeutic …

Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and Clinical …

J Ansary, F Giampieri, TY Forbes-Hernandez, L Regolo… - Molecules, 2021 - mdpi.com
In recent times, scientific attention has been paid to different foods and their bioactive
components for the ability to inhibit the onset and progress of different types of cancer …

Potential of carvacrol and thymol in reducing biofilm formation on technical surfaces

M Walczak, M Michalska-Sionkowska, D Olkiewicz… - Molecules, 2021 - mdpi.com
Polyvinyl chloride (PVC), polypropylene (PP), polyethylene (PE), and stainless steel (SS)
are commonly used in medicine and food production technologies. During contact with …

Comparative analysis of the protective effects of curcumin and N-acetyl cysteine against paracetamol-induced hepatic, renal, and testicular toxicity in Wistar rats

ZK El-Maddawy, YS El-Sayed - Environmental science and pollution …, 2018 - Springer
This study aimed to investigate the possible protective role of curcumin (CUR) vs. N-acetyl
cysteine (NAC) against paracetamol (PCM)-induced oxidative damage and impairment of …

Protective effects of natural antioxidants on inflammatory bowel disease: thymol and its pharmacological properties

Y Liu, H Yan, B Yu, J He, X Mao, J Yu, P Zheng… - Antioxidants, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a gastrointestinal disease that involves chronic mucosal
or submucosal lesions that affect tissue integrity. Although IBD is not life-threatening, it …

In vitro Models and On-Chip Systems: Biomaterial Interaction Studies With Tissues Generated Using Lung Epithelial and Liver Metabolic Cell Lines

M Nikolic, T Sustersic, N Filipovic - Frontiers in bioengineering and …, 2018 - frontiersin.org
In vitro models are very important in medicine and biology, because they provide an insight
into cells' and microorganisms' behavior. Since these cells and microorganisms are isolated …

Establishing a 3D in vitro hepatic model mimicking physiologically relevant to in vivo state

HK Kang, M Sarsenova, DH Kim, MS Kim, JY Lee… - Cells, 2021 - mdpi.com
Three-dimensional (3D) bioprinting is a promising technology to establish a 3D in vitro
hepatic model that holds great potential in toxicological evaluation. However, in current …