Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides …

CC Willhite, NA Karyakina, RA Yokel… - Critical reviews in …, 2014 - Taylor & Francis
Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most
abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); …

Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis

A Gasmi, M Peana, M Arshad, M Butnariu… - Archives of …, 2021 - Springer
A fundamental metabolic feature of cancerous tissues is high glucose consumption. The rate
of glucose consumption in a cancer cell can be 10–15 times higher than in normal cells …

Dysfunctional mitochondrial bioenergetics and the pathogenesis of hepatic disorders

C Auger, A Alhasawi, M Contavadoo… - Frontiers in cell and …, 2015 - frontiersin.org
The liver is involved in a variety of critical biological functions including the homeostasis of
glucose, fatty acids, amino acids, and the synthesis of proteins that are secreted in the blood …

Biochemical pathways to α-ketoglutarate, a multi-faceted metabolite

F Legendre, A MacLean, VP Appanna… - World Journal of …, 2020 - Springer
Abstract α-Ketoglutarate (AKG) also known as 2-oxoglutarate is an essential metabolite in
virtually all organisms as it participates in a variety of biological processes including anti …

Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins

RJ Mailloux, ME Harper - Trends in Endocrinology & Metabolism, 2012 - cell.com
Fifty years since Peter Mitchell proposed the theory of chemiosmosis, the transformation of
cellular redox potential into ATP synthetic capacity is still a widely recognized function of …

[HTML][HTML] The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what …

G Morris, BK Puri, RE Frye - Metabolic brain disease, 2017 - Springer
The conceptualisation of autistic spectrum disorder and Alzheimer's disease has undergone
something of a paradigm shift in recent years and rather than being viewed as single …

Aluminum‐Induced Entropy in Biological Systems: Implications for Neurological Disease

CA Shaw, S Seneff, SD Kette, L Tomljenovic… - Journal of …, 2014 - Wiley Online Library
Over the last 200 years, mining, smelting, and refining of aluminum (Al) in various forms
have increasingly exposed living species to this naturally abundant metal. Because of its …

Metabolic reengineering invoked by microbial systems to decontaminate aluminum: implications for bioremediation technologies

C Auger, S Han, VP Appanna, SC Thomas… - Biotechnology …, 2013 - Elsevier
As our reliance on aluminum (Al) increases, so too does its presence in the environment and
living systems. Although generally recognized as safe, its interactions with most living …

Chlorogenic acid protects against aluminium-induced cytotoxicity through chelation and antioxidant actions in primary hippocampal neuronal cells

X Wang, X Fan, S Yuan, W Jiao, B Liu, J Cao… - Food & function, 2017 - pubs.rsc.org
Chlorogenic acid (CGA), a major polyphenolic component of many plants, displays
antioxidant and neuroprotective properties in neurodegenerative diseases. To investigate …

Empirical data confirm autism symptoms related to aluminum and acetaminophen exposure

S Seneff, RM Davidson, J Liu - Entropy, 2012 - mdpi.com
Autism is a condition characterized by impaired cognitive and social skills, associated with
compromised immune function. The incidence is alarmingly on the rise, and environmental …