The CCN2/CTGF interactome: an approach to understanding the versatility of CCN2/CTGF molecular activities

V Zaykov, B Chaqour - Journal of cell communication and signaling, 2021 - Springer
Abstract Cellular communication network 2 (CCN2), also known as connective tissue growth
factor (CTGF) regulates diverse cellular processes, some at odds with others, including …

Changing subplate circuits: Early activity dependent circuit plasticity

D Mukherjee, PO Kanold - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Early neural activity in the developing sensory system comprises spontaneous bursts of
patterned activity, which is fundamental for sculpting and refinement of immature cortical …

Modified CFBP-bFGF targeting to ischemic brain promoted the functional recovery of cerebral ischemia

J Deng, X Zhang, M Yin, W Cao, B Zhang, Q Liu… - Journal of Controlled …, 2023 - Elsevier
The cerebral ischemia was one of the most common causes of disability and death
worldwide. Basic fibroblast growth factor (bFGF) was reported to have neuroprotective …

Deprivation of muscleblind-like proteins causes deficits in cortical neuron distribution and morphological changes in dendritic spines and postsynaptic densities

KY Lee, HC Chang, C Seah, LJ Lee - Frontiers in Neuroanatomy, 2019 - frontiersin.org
Myotonic dystrophy (Dystrophia Myotonica; DM) is the most common adult-onset muscular
dystrophy and its brain symptoms seriously affect patients' quality of life. It is caused by …

Enhanced glaucomatous damage accompanied by glial response in a new multifactorial mouse model

S Reinehr, RM Girbig, KK Schulte, J Theile… - Frontiers in …, 2023 - frontiersin.org
Introduction Glaucoma is a complex, multifactorial neurodegenerative disease, which can
lead to blindness if left untreated. It seems that, among others, immune processes, elevated …

Distinct distribution of subplate neuron subtypes between the sensory cortices during the early postnatal period

M Chang, S Nehs, Z Xu… - Journal of Comparative …, 2024 - Wiley Online Library
Subplate neurons (SpNs) are a heterogeneous neuronal population actively involved in
early cortical circuit formation. In rodents, many SpNs survive and form layer 6b. The …

Mice lacking connective tissue growth factor in the forebrain exhibit delayed seizure response, reduced c-Fos expression and different microglial phenotype following …

PF Siow, CY Tsao, HC Chang, CY Chen, IS Yu… - International Journal of …, 2020 - mdpi.com
Connective tissue growth factor (CTGF) plays important roles in the development and
regeneration of the connective tissue, yet its function in the nervous system is still not clear …

Elevated reactive aggression in forebrain‐specific Ccn2 knockout mice

HC Chang, CH Ng, YF Chen, YC Wang… - Journal of Cell …, 2024 - Wiley Online Library
Cellular communication network factor 2 (CCN2) is a matricellular protein that plays
important roles in connective tissue. CCN2 is also expressed in the nervous system; …

结缔组织生长因子在神经系统中的功能与作用

马思聪, 陈晶, 李云庆 - 中国组织工程研究, 2024 - cjter.com
结缔组织生长因子在神经系统中的功能与作用 Page 1 Chinese Journal of Tissue Engineering
Research|Vol 28|No.4|February 2024|615 中国组织工程研究 Chinese Journal of Tissue …

A consensus definition for deep layer 6 excitatory neurons in mouse neocortex

SJ Kim, TA Babola, K Lee, CJ Matney, AC Spiegel… - bioRxiv, 2024 - biorxiv.org
To understand neocortical function, we must first define its cell types. Recent studies indicate
that neurons in the deepest cortical layer play roles in mediating thalamocortical interactions …