A review on comparative studies addressing exosome isolation methods from body fluids

TS Martins, M Vaz, AG Henriques - Analytical and Bioanalytical Chemistry, 2023 - Springer
Exosomes emerged as valuable sources of disease biomarkers and new therapeutic tools.
However, extracellular vesicles isolation with exosome-like characteristics from certain …

Preservation and storage stability of extracellular vesicles for therapeutic applications

A Jeyaram, SM Jay - The AAPS journal, 2018 - Springer
Abstract Recently, extracellular vesicles (EVs)—including exosomes, microvesicles, and
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …

Optimized exosome isolation protocol for cell culture supernatant and human plasma

RJ Lobb, M Becker, S Wen Wen… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles represent a rich source of novel biomarkers in the diagnosis and
prognosis of disease. However, there is currently limited information elucidating the most …

Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper

T Lener, M Gimona, L Aigner, V Börger… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …

Exosome isolation from distinct biofluids using precipitation and column-based approaches

T Soares Martins, J Catita, I Martins Rosa… - PloS one, 2018 - journals.plos.org
The potential of exosomes as biomarker resources for diagnostics, prognostics and even for
therapeutics is an area of intense research. Despite the various approaches available, there …

Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular …

J Lötvall, AF Hill, F Hochberg, EI Buzás… - Journal of …, 2014 - Wiley Online Library
Secreted membrane‐enclosed vesicles, collectively called extracellular vesicles (EVs),
which include exosomes, ectosomes, microvesicles, microparticles, apoptotic bodies and …

Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

J Van Deun, P Mestdagh, R Sormunen… - Journal of …, 2014 - Taylor & Francis
Despite an enormous interest in the role of extracellular vesicles, including exosomes, in
cancer and their use as biomarkers for diagnosis, prognosis, drug response and recurrence …

Concise review: developing best-practice models for the therapeutic use of extracellular vesicles

AT Reiner, KW Witwer, BWM Van Balkom… - Stem cells …, 2017 - academic.oup.com
Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as
therapeutic entities, particularly in stem cell-related approaches, has underlined the need for …

High-speed centrifugation induces aggregation of extracellular vesicles

R Linares, S Tan, C Gounou, N Arraud… - Journal of extracellular …, 2015 - Taylor & Francis
Plasma and other body fluids contain cell-derived extracellular vesicles (EVs), which
participate in physiopathological processes and have potential biomedical applications. In …