Emerging risk biomarkers in cardiovascular diseases and disorders

RK Upadhyay - Journal of lipids, 2015 - Wiley Online Library
Present review article highlights various cardiovascular risk prediction biomarkers by
incorporating both traditional risk factors to be used as diagnostic markers and recent …

MRI of rod cell compartment-specific function in disease and treatment in vivo

BA Berkowitz, D Bissig, R Roberts - Progress in retinal and eye research, 2016 - Elsevier
Rod cell oxidative stress is a major pathogenic factor in retinal disease, such as diabetic
retinopathy (DR) and retinitis pigmentosa (RP). Personalized, non-destructive, and targeted …

Photobiomodulation mitigates diabetes-induced retinopathy by direct and indirect mechanisms: evidence from intervention studies in pigmented mice

A Saliba, Y Du, H Liu, S Patel, R Roberts… - PloS one, 2015 - journals.plos.org
Objective Daily application of far-red light from the onset of diabetes mitigated diabetes-
induced abnormalities in retinas of albino rats. Here, we test the hypothesis that …

Oxidative stress and light-evoked responses of the posterior segment in a mouse model of diabetic retinopathy

BA Berkowitz, EM Grady, N Khetarpal… - … & visual science, 2015 - iovs.arvojournals.org
Purpose.: To test the hypothesis that in a mouse model of diabetic retinopathy, oxidative
stress is linked with impaired light-evoked expansion of choroidal thickness and subretinal …

[HTML][HTML] Measuring in vivo free radical production by the outer retina

BA Berkowitz, BX Bredell, C Davis… - … & visual science, 2015 - arvojournals.org
Purpose: Excessive and continuously produced free radicals in the outer retina are
implicated in retinal aging and the pathogenesis of sight-threatening retinopathies, yet …

[HTML][HTML] Dynamic responses in retinal vessel caliber with flicker light stimulation and risk of diabetic retinopathy and its progression

LS Lim, LH Ling, PG Ong, W Foulds… - … & visual science, 2017 - arvojournals.org
Purpose: This study investigated the associations between the responses of retinal vessels
to flickering light and the incidence and progression of diabetic retinopathy (DR). Methods: A …

In Vivo Evaluation of the Visual Pathway in Streptozotocin-Induced Diabetes by Diffusion Tensor MRI and Contrast Enhanced MRI

S Kancherla, WJ Kohler, Y Van Der Merwe, KC Chan - PloS one, 2016 - journals.plos.org
Visual function has been shown to deteriorate prior to the onset of retinopathy in some
diabetic patients and experimental animal models. This suggests the involvement of the …

Confirming a prediction of the calcium hypothesis of photoreceptor aging in mice

BA Berkowitz, EM Grady, R Roberts - Neurobiology of aging, 2014 - Elsevier
Prior work in healthy rats supported a calcium hypothesis of photoreceptor aging, wherein
progressive age-related declines in photopic vision are explainable by the extent of earlier …

[HTML][HTML] Systemic retinaldehyde treatment corrects retinal oxidative stress, rod dysfunction, and impaired visual performance in diabetic mice

BA Berkowitz, TS Kern, D Bissig, P Patel… - … & visual science, 2015 - arvojournals.org
Purpose: Diabetes appears to induce a visual cycle defect because rod dysfunction is
correctable with systemic treatment of the visual cycle chromophore 11-cis-retinaldehyde …

Manganese enhanced magnetic resonance imaging (MEMRI): a powerful new imaging method to study tinnitus

AT Cacace, T Brozoski, B Berkowitz, C Bauer… - Hearing research, 2014 - Elsevier
Manganese enhanced magnetic resonance imaging (MEMRI) is a method used primarily in
basic science experiments to advance the understanding of information processing in …