Skeletal muscle is a malleable tissue capable of altering the type and amount of protein in
response to disruptions to cellular homeostasis. The process of exerciseinduced adaptation …

When human skeletal muscle is exposed to exercise training, the outcomes, in terms of
physiological adaptation, are unpredictable. The significance of this fact has long been …

The molecular mechanisms underlying the response to exercise and inactivity are not fully
understood. We propose an innovative approach to profile the skeletal muscle transcriptome …

This chapter is devoted to the role of genetic variation and gene-exercise interactions in the
biology of adaptation to exercise. There is evidence from genetic epidemiology research that …

For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Summary Type 2 (non-insulin-dependent) diabetes mellitus is a progressive metabolic
disorder arising from genetic and environmental factors that impair beta cell function and …

There is a considerable body of evidence gathered from studies over the past half a century
indicating that a high level of physical activity and a moderately high or high degree of …

The aim of the HERITAGE Family Study was to investigate individual differences in response
to a standardized endurance exercise program, the role of familial aggregation, and the …

Physical activity plays an important role in preventing chronic disease in adults and the
elderly. Exercise has beneficial effects on the nervous system, including at the …

Skeletal muscle displays enormous plasticity to respond to contractile activity with muscle
from strength-(ST) and endurance-trained (ET) athletes representing diverse states of the …