Deep learning in cancer pathology: a new generation of clinical biomarkers

A Echle, NT Rindtorff, TJ Brinker, T Luedde… - British journal of …, 2021 - nature.com
Clinical workflows in oncology rely on predictive and prognostic molecular biomarkers.
However, the growing number of these complex biomarkers tends to increase the cost and …

Artificial intelligence for digital and computational pathology

AH Song, G Jaume, DFK Williamson, MY Lu… - Nature Reviews …, 2023 - nature.com
Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence,
including deep learning, have boosted the field of computational pathology. This field holds …

[HTML][HTML] Quality control stress test for deep learning-based diagnostic model in digital pathology

B Schömig-Markiefka, A Pryalukhin, W Hulla… - Modern Pathology, 2021 - Elsevier
Digital pathology provides a possibility for computational analysis of histological slides and
automatization of routine pathological tasks. Histological slides are very heterogeneous …

[HTML][HTML] Predictive uncertainty estimation for out-of-distribution detection in digital pathology

J Linmans, S Elfwing, J van der Laak, G Litjens - Medical Image Analysis, 2023 - Elsevier
Abstract Machine learning model deployment in clinical practice demands real-time risk
assessment to identify situations in which the model is uncertain. Once deployed, models …

Deep learning for bone marrow cell detection and classification on whole-slide images

CW Wang, SC Huang, YC Lee, YJ Shen, SI Meng… - Medical Image …, 2022 - Elsevier
Bone marrow (BM) examination is an essential step in both diagnosing and managing
numerous hematologic disorders. BM nucleated differential count (NDC) analysis, as part of …

[HTML][HTML] Combining CNN-based histologic whole slide image analysis and patient data to improve skin cancer classification

J Höhn, E Krieghoff-Henning, TB Jutzi… - European Journal of …, 2021 - Elsevier
Background Clinicians and pathologists traditionally use patient data in addition to clinical
examination to support their diagnoses. Objectives We investigated whether a combination …

[HTML][HTML] Multiple instance learning for digital pathology: A review of the state-of-the-art, limitations & future potential

M Gadermayr, M Tschuchnig - Computerized Medical Imaging and …, 2024 - Elsevier
Digital whole slides images contain an enormous amount of information providing a strong
motivation for the development of automated image analysis tools. Particularly deep neural …

Artificial intelligence in dermatopathology: Diagnosis, education, and research

A Wells, S Patel, JB Lee… - Journal of cutaneous …, 2021 - Wiley Online Library
Artificial intelligence (AI) utilizes computer algorithms to carry out tasks with human‐like
intelligence. Convolutional neural networks, a type of deep learning AI, can classify basal …

[HTML][HTML] Deep learning in computational dermatopathology of melanoma: A technical systematic literature review

D Sauter, G Lodde, F Nensa, D Schadendorf… - Computers in biology …, 2023 - Elsevier
Deep learning (DL) has become one of the major approaches in computational
dermatopathology, evidenced by a significant increase in this topic in the current literature …

Machine learning in oncology: what should clinicians know?

M Nagy, N Radakovich, A Nazha - JCO Clinical Cancer Informatics, 2020 - ascopubs.org
The volume and complexity of scientific and clinical data in oncology have grown markedly
over recent years, including but not limited to the realms of electronic health data …