The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …

We provide a comprehensive classification of the proteoglycan gene families and respective
protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular …

Dynamic interactions between growth factors and extracellular matrix (ECM) are integral to
wound healing. These interactions take several forms that may be categorized as direct or …

Introduction• Perlecan: a pro‐angiogenic proteoglycan• Endorepellin, a C‐terminal fragment
of perlecan with anti‐angiogenic activity• Syndecans in cancer biology• Glypicans and the …

Tendon healing is a complex and highly-regulated process that is initiated, sustained and
eventually terminated by a large number and variety of molecules. Growth factors represent …

Silk fibroin (SF), a naturally occurring protein polymer, has several unique properties making
it a favorable matrix for the incorporation and delivery of a range of therapeutic agents. SF is …

Cell-surface/extracellular-matrix heparan-sulphate glycosaminoglycans (HSGAGs) are
complex polysaccharides that are ubiquitous in nature, and that regulate several aspects of …

Abstract The Cbfa1/Runx2 is an important transcription factor necessary for osteoblast
differentiation and bone formation. However, the signaling pathways regulating Runx2 …

Pterygium is a common ocular surface disease apparently only observed in humans.
Chronic UV exposure is a widely accepted aetiological factor in the pathogenesis of this …

Non-thermal dielectric barrier discharge plasma is being developed for a wide range of
medical applications, including wound healing, blood coagulation, and malignant cell …