Advances in drug delivery-based therapeutic strategies for renal fibrosis treatment

S Huang, H Lu, J Chen, C Jiang, G Jiang… - Journal of Materials …, 2024 - pubs.rsc.org
Renal fibrosis is the result of all chronic kidney diseases and is becoming a major global
health hazard. Currently, traditional treatments for renal fibrosis are difficult to meet clinical …

Zinc: An element of extensive medical importance

N Parveen, MO Ansari, MF Ahmad, S Jameel… - … Medicine Research and …, 2017 - Elsevier
Zinc is an element of great biological significance. Many biochemical processes cannot
occur without zinc as it is required for large number of physiological functions. It plays an …

ZIP14 is involved in iron deposition and triggers ferroptosis in diabetic nephropathy

K Wu, L Fei, X Wang, Y Lei, L Yu, W Xu, J Chen… - Metallomics, 2022 - academic.oup.com
Ferroptosis is caused by lipid peroxidation and iron accumulation and can cause cell death.
Abnormally expressed iron transporters are involved in ferroptosis in a variety of diseases …

[HTML][HTML] Associations of multiple plasma metals with chronic kidney disease in patients with diabetes

R Wang, T Long, J He, Y Xu, Y Wei, Y Zhang… - Ecotoxicology and …, 2022 - Elsevier
Highlights•The logistic, LASSO, and BKMR models were used to examine the
associations.•Plasma Ti, Cd, and Pb were negatively associated with CKD in …

Renal handling of zinc in chronic kidney disease patients and the role of circulating zinc levels in renal function decline

K Damianaki, JM Lourenco, P Braconnier… - Nephrology Dialysis …, 2020 - academic.oup.com
Background Zinc deficiency is commonly encountered in chronic kidney disease (CKD). The
aims of this study were to assess whether zinc deficiency was related to increased renal …

Zinc, copper, and oxysterol levels in patients with type 1 and type 2 diabetes mellitus

A Samadi, SY Isikhan, AA Tinkov, I Lay, MD Doşa… - Clinical Nutrition, 2020 - Elsevier
Background The present study has the objective to assess the zinc (Zn), copper (Cu), and
oxysterols plasma levels in type 1 (DM1)(n= 26) and type 2 (DM2)(n= 80) diabetes patients …

Role of zinc in diabetic kidney disease

G Gembillo, L Visconti, AE Giuffrida, V Labbozzetta… - Nutrients, 2022 - mdpi.com
Diabetic Kidney Disease (DKD) represents the most common cause of Chronic Kidney
Disease (CKD) in developed countries. Approximately 30% to 40% of diabetes mellitus (DM) …

Zinc deficiency, plasma fatty acid profile and desaturase activities in hemodialysis patients: is supplementation necessary?

M Takic, M Zekovic, B Terzic, A Stojsavljevic… - Frontiers in …, 2021 - frontiersin.org
Background: Desaturation and elongation are critical processes in endogenous metabolic
fatty acid pathways. Zinc (Zn) is a cofactor for desaturases and elongases enzymes. There is …

Zinc status biomarkers and cardiometabolic risk factors in metabolic syndrome: a case control study

EPS Freitas, ATO Cunha, SLS Aquino, LFC Pedrosa… - Nutrients, 2017 - mdpi.com
Metabolic syndrome (MS) involves pathophysiological alterations that might compromise
zinc status. The aim of this study was to evaluate zinc status biomarkers and their …

Relationships of the trace elements zinc and magnesium with diabetic nephropathy-associated renal functional damage in patients with type 2 diabetes mellitus

J Feng, H Wang, Z Jing, Y Wang, W Wang… - Frontiers in …, 2021 - frontiersin.org
Zinc (Zn) and magnesium (Mg) are essential trace elements in humans. Their deficiency
may be associated with inflammation and oxidative stress (OS) in patients with diabetic …