MRI findings of disc degeneration are more prevalent in adults with low back pain than in asymptomatic controls: a systematic review and meta-analysis
W Brinjikji, FE Diehn, JG Jarvik… - American Journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Imaging features of spine degeneration are common in
symptomatic and asymptomatic individuals. We compared the prevalence of MR imaging …
symptomatic and asymptomatic individuals. We compared the prevalence of MR imaging …
Pathobiology of Modic changes
Purpose Low back pain (LBP) is the most disabling condition worldwide. Although LBP
relates to different spinal pathologies, vertebral bone marrow lesions visualized as Modic …
relates to different spinal pathologies, vertebral bone marrow lesions visualized as Modic …
An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations
L Manchikanti, S Abdi, S Atluri, RM Benyamin… - Pain …, 2013 - search.proquest.com
OBJECTIVE: To develop evidence-based clinical practice guidelines for interventional
techniques in the diagnosis and treatment of chronic spinal pain. METHODOLOGY …
techniques in the diagnosis and treatment of chronic spinal pain. METHODOLOGY …
Modic changes of the lumbar spine: prevalence, risk factors, and association with disc degeneration and low back pain in a large-scale population-based cohort
FPS Mok, D Samartzis, J Karppinen, DYT Fong… - The spine journal, 2016 - Elsevier
Abstract Background Context Modic changes (MC) are bone marrow lesions on magnetic
resonance imaging (MRI), suggestive of being associated with low back pain (LBP). Data on …
resonance imaging (MRI), suggestive of being associated with low back pain (LBP). Data on …
Fat infiltration of paraspinal muscles is associated with low back pain, disability, and structural abnormalities in community-based adults
Background context Low back pain and disability are major public health problems and may
be related to paraspinal muscle abnormalities, such as a reduction in muscle size and …
be related to paraspinal muscle abnormalities, such as a reduction in muscle size and …
Modic changes—their associations with low back pain and activity limitation: a systematic literature review and meta-analysis
C Herlin, P Kjaer, A Espeland, JS Skouen… - PloS one, 2018 - journals.plos.org
Background Previous systematic reviews have reported positive associations between
Modic changes (MCs) and low back pain (LBP), but due to their narrow scope and new …
Modic changes (MCs) and low back pain (LBP), but due to their narrow scope and new …
Vertebral endplate signal changes (Modic change): a systematic literature review of prevalence and association with non-specific low back pain
TS Jensen, J Karppinen, JS Sorensen… - European Spine …, 2008 - Springer
The prevalence of “vertebral endplate signal changes”(VESC) and its association with low
back pain (LBP) varies greatly between studies. This wide range in reported prevalence …
back pain (LBP) varies greatly between studies. This wide range in reported prevalence …
The American Society of Pain and Neuroscience (ASPN) evidence-based clinical guideline of interventional treatments for low back pain
D Sayed, J Grider, N Strand, JM Hagedorn… - Journal of Pain …, 2022 - Taylor & Francis
Introduction Painful lumbar spinal disorders represent a leading cause of disability in the US
and worldwide. Interventional treatments for lumbar disorders are an effective treatment for …
and worldwide. Interventional treatments for lumbar disorders are an effective treatment for …
The modic vertebral endplate and marrow changes: pathologic significance and relation to low back pain and segmental instability of the lumbar spine
R Rahme, R Moussa - American Journal of Neuroradiology, 2008 - Am Soc Neuroradiology
Two decades following their description, the significance of Modic vertebral endplate and
marrow changes remains a matter of debate. These changes are closely related to the …
marrow changes remains a matter of debate. These changes are closely related to the …
Contribution of the endplates to disc degeneration
AJ Fields, A Ballatori, EC Liebenberg… - Current molecular biology …, 2018 - Springer
Abstract Purpose of Review The endplates form the interface between the rigid vertebral
bodies and compliant intervertebral discs. Proper endplate function involves a balance …
bodies and compliant intervertebral discs. Proper endplate function involves a balance …