Background Epigenetic modifications of the genome, such as DNA methylation and histone
modifications, have been reported to play a role in processes underlying cardiovascular …

Ischemic stroke (IS) is a multifactorial and heterogeneous neurological disorder with high
rate of death and long-term impairment. Despite years of studies, there are still no stroke …

Stroke is a leading cause of morbidity and mortality worldwide. It inflicts immeasurable
suffering on patients and their loved ones and carries an immense social cost. Efforts to …

Background and aims The aim of this study was to perform a systematic review of the
association between DNA methylation and coronary heart disease (CHD) or related …

Ischemic stroke is a sudden loss of brain function due to the reduction of blood flow. Brain
tissues cease to function with subsequent activation of the ischemic cascade. Metabolomics …

The prevalence and incidence of stroke rises with life expectancy. However, except for the
use of recombinant tissue-type plasminogen activator, the translation of new therapies for …

Ischemic stroke is associated with various physiological and pathological processes
including neuronal apoptosis. Growth-arrest-specific transcript 5 (GAS5), a long non-coding …

Background High blood pressure is a major risk factor for cardiovascular disease and is
influenced by both environmental and genetic factors. Epigenetic processes including DNA …

Methylenetetrahydrofolate reductase (MTHFR) is a pivotal enzyme in the one-carbon
metabolism, a metabolic pathway required for DNA synthesis and methylation reactions …

We collected blood DNA from 120 late-onset Alzheimer's disease (AD) patients and 115
healthy matched controls and analysed the methylation levels of genes involved in amyloid …